Reaction profile

The FDA adverse-event record for other ear disorder nos

675 FDA reports name other ear disorder nos, a high-volume reaction in the CVM extract (VeDDRA 1667). Plate stamps and neighbourhood peers follow.

#527 of 2,481
by report volume (all reactions)
675
reports citing this reaction
5.2%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Other ear disorder NOS has 675 reports now versus 667 in that prior snapshot: 8 more (1.2%).

Report change
+8
Death-coded reports
+0
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Other ear disorder NOS changes

FDA AER · VeDDRA plate

Code 1667 VOL-MID

VOL-MID · DEATH-PAR · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 675 reports
  • DEATH-PAR 5.2%
  • UPPER-Q #527/2481
  • PHOTO-FINISH Involuntary defecation
  • SPECIES-DOG Dog · 569
  • DRUG-LEAD Milbemycin Oxime… · 149
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Involuntary defecation (±2 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Other ear disorder NOS

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Other ear disorder NOS · thi…675Involuntary defecation · near673Respiratory arrest · near673Unrelated death · near673Lack of efficacy (pro… · near670Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Other ear disorder NOS

Other ear disorder NOS: low death-coded share in the FDA AER plate

Signature read: 675 reports place Other ear disorder NOS in the upper third of FDA AER volume (#527 of 2,481). Report volume is upper-third scale: 675 named reports in the openFDA extract. Death-coded share is lower-third: 35 of 675 reports (5.2% of named reports). Nearest volume peer: Involuntary defecation (±2 reports). Lead species Dog (569). Lead co-reported drug Milbemycin Oxime + Spinosad (149).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 569
Cat 93
Human 6
Cattle 5
Horse 2

Breeds Most Affected

Retriever - Labrador 68
Domestic Shorthair 52
Crossbred Canine/dog 41
Retriever - Golden 31
Shepherd Dog - German 30
Chihuahua 23
Shih Tzu 23
Boxer (German Boxer) 22
Pit Bull 19
Terrier - Yorkshire 16

Associated Drugs

Milbemycin Oxime + Spinosad 149
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 68
Betamethasone + Florfenicol + Terbinafine 67
Milbemycin Oxime + Praziquantel 43
Afoxolaner 35
Oclacitinib Maleate 34
Spinosad 30
Maropitant Citrate 28
Carprofen 27
Gabapentin 25
Prednisone 23
Genta/Momet/Clotrim Ear Oint 20
Selamectin 19
Enrofloxacin 19
Florfenicol/Terbinafine Hydrochloride/Mometasone Furoate 19
Miconazole + Polymyxin B + Prednisolone 18
Ear Cleaner (Unknown) 18
Rabies Vaccine 17
Ketoconazole 14
Ivermectin + Pyrantel As Pamoate Salt 14

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Other ear disorder NOS, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (675 here).

Similar death-coded share

Nearest other reactions by death-coded share (5.2% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Other ear disorder NOS (#527 of 2,481 by report volume); death-coded 5.2%. PlainBreed reaction plate · report volume stamp 675 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →