Reaction profile

The FDA adverse-event record for ineffective, whips

2,007 FDA adverse-event reports reference ineffective, whips (VeDDRA 99158). See the species, breeds, and drugs most associated with it below.

2,007
reports citing this reaction
0.3%
death-coded share
Dog
most-affected species
Ivermectin + Pyrantel As Pamoate Salt
most-associated drug
Verify with FDA CVM →
2,007
Total Reports
6
Deaths
0.3%
Death Rate

Species Most Affected

Dog 2,000
Pig 2
Cattle 2
Cat 2
Other Canids 1

Breeds Most Affected

Retriever - Labrador 253
Retriever - Golden 150
Crossbred Canine/dog 129
Shepherd Dog - German 105
Beagle 85
Shepherd Dog - Australian 59
Dachshund (unspecified) 58
Dog (unknown) 54
Pit Bull 51
Collie - Border 49

Associated Drugs

Ivermectin + Pyrantel As Pamoate Salt 767
Milbemycin Oxime + Praziquantel 515
Milbemycin Oxime + Spinosad 190
Moxidectin 154
Lufenuron + Milbemycin Oxime 151
Imidacloprid + Moxidectin 90
Milbemycin Oxime 75
Lufenuron + Milbemycin Oxime + Praziquantel 67
Milbemycin Oxime, Lufenuron 54
Selamectin 28
Afoxolaner 20
Fluralaner 16
Fenbendazole 15
Milbemcyin Oxime, Lufenuron, Praziquantel 14
Ivermectin + Pyrantel 13
Febantel + Praziquantel + Pyrantel Pamoate 13
Milbemycin/Lufenuron Tablets 13
Sarolaner 10
Milbemycin/Lufenuron/Pzq Chew 8
Ivermectin 7

INEFFECTIVE, WHIPS Reaction Insights

2,007 reports name INEFFECTIVE, WHIPS; 6 recorded a death outcome (0.3% of reported events, not a population-level mortality rate). VeDDRA code: 99158.

By species: Dog (2,000 reports), Pig (2 reports), Cattle (2 reports). By breed: Retriever - Labrador (253), Retriever - Golden (150), Crossbred Canine/dog (129).

Most co-reported drugs: Ivermectin + Pyrantel As Pamoate Salt (767 reports), Milbemycin Oxime + Praziquantel (515 reports), Milbemycin Oxime + Spinosad (190 reports), Moxidectin (154 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.