Reaction profile

The FDA adverse-event record for male reproductive tract disorder nos

60 FDA adverse-event reports reference male reproductive tract disorder nos (VeDDRA 767). See the species, breeds, and drugs most associated with it below.

60
reports citing this reaction
10.0%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
Verify with FDA CVM →
60
Total Reports
6
Deaths
10.0%
Death Rate

Species Most Affected

Dog 42
Cattle 8
Horse 4
Cat 2
Pig 1
Human 1
Chicken 1
Hedgehog 1

Breeds Most Affected

Shepherd Dog - German 8
Retriever - Labrador 5
Dachshund (unspecified) 4
Retriever - Golden 2
Horse (unknown) 2
Cattle (unknown) 2
Spaniel - King Charles Cavalier 2
Sheepdog - Shetland 2
Schnauzer - Miniature 2
Terrier - Yorkshire 2

Associated Drugs

Milbemycin Oxime + Spinosad 9
Carprofen 5
Ivermectin 3
Spinosad 3
Oclacitinib Maleate 3
Ivermectin, Pyrantel 2
Ponazuril 2
Monensin Sodium 2
Nitenpyram 2
Famotidine 2
Methocarbamol 2
Imidacloprid + Moxidectin 2
Febantel + Praziquantel + Pyrantel Pamoate 2
Milbemycin, Lufenuron 1
Zeranol 1
Hyaluronate Sodium 1
Narasin 1
Amoxicillin, Clavulanate 1
Marbofloxacin 1
Moxidectin 1

Male reproductive tract disorder NOS Reaction Insights

60 reports name Male reproductive tract disorder NOS; 6 recorded a death outcome (10.0% of reported events, not a population-level mortality rate). VeDDRA code: 767.

By species: Dog (42 reports), Cattle (8 reports), Horse (4 reports). By breed: Shepherd Dog - German (8), Retriever - Labrador (5), Dachshund (unspecified) (4).

Most co-reported drugs: Milbemycin Oxime + Spinosad (9 reports), Carprofen (5 reports), Ivermectin (3 reports), Spinosad (3 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.