Reaction profile

The FDA adverse-event record for medication error

1,235 FDA adverse-event reports reference medication error (VeDDRA 2282). See the species, breeds, and drugs most associated with it below.

1,235
reports citing this reaction
3.9%
death-coded share
Dog
most-affected species
Fluralaner Spot-On Solution
most-associated drug
Verify with FDA CVM →
1,235
Total Reports
48
Deaths
3.9%
Death Rate

Species Most Affected

Dog 817
Human 195
Cat 190
Cattle 14
Horse 8
Unknown 4
Sheep 2
Other 1
Alpaca 1
Pig 1

Breeds Most Affected

Unknown 208
Crossbred Canine/dog 144
Domestic Shorthair 117
Retriever - Labrador 61
Dog (unknown) 59
Chihuahua 43
Shih Tzu 28
Terrier - Yorkshire 28
Retriever - Golden 25
Cat (unknown) 23

Associated Drugs

Fluralaner Spot-On Solution 204
Insulin Injectable Vial 152
Fluralaner 13.64% 12-Week Chew 135
Fluralaner Chew Tablets 124
Ivermectin + Pyrantel 87
Trilostane 74
Carprofen 57
Fluralaner/Moxidectin Spot-On 49
Fenbendazol Granules 33
Mirtazapine 33
Prednisone 32
Milbemycin Oxime + Spinosad 29
Desoxycorticosterone Pivalate 27
Milbemycin Oxime + Praziquantel 23
Genta/Momet/Clotrim Ear Oint 21
Grapiprant 20
Milbemycin/Lufenuron Tablets 16
Desoxycortone Pivalate 16
Orbiflox/Momet/Posaco Eardrops 13
Estriol Tablets 12

Medication error Reaction Insights

1,235 reports name Medication error; 48 recorded a death outcome (3.9% of reported events, not a population-level mortality rate). VeDDRA code: 2282.

By species: Dog (817 reports), Human (195 reports), Cat (190 reports). By breed: Unknown (208), Crossbred Canine/dog (144), Domestic Shorthair (117).

Most co-reported drugs: Fluralaner Spot-On Solution (204 reports), Insulin Injectable Vial (152 reports), Fluralaner 13.64% 12-Week Chew (135 reports), Fluralaner Chew Tablets (124 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.