Reaction profile

The FDA adverse-event record for intestinal stasis

66 FDA adverse-event reports reference intestinal stasis (VeDDRA 1066). See the species, breeds, and drugs most associated with it below.

66
reports citing this reaction
21.2%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
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66
Total Reports
14
Deaths
21.2%
Death Rate

Species Most Affected

Dog 50
Cat 9
Horse 4
Chinchilla 1
Pig 1
Camel 1

Breeds Most Affected

Domestic Shorthair 7
Retriever - Labrador 6
Crossbred Canine/dog 5
Retriever - Golden 5
Maltese 3
Thoroughbred 2
Dog (unknown) 2
Chihuahua 2
Shepherd Dog - German 2
Terrier - Yorkshire 2

Associated Drugs

Milbemycin Oxime + Spinosad 15
Maropitant Citrate 6
Buprenorphine 5
Isoflurane 5
Ketamine 4
Tramadol 4
Rabies Vaccine 3
Propofol 3
Acepromazine 3
Carprofen 3
Grapiprant 3
Febantel + Praziquantel + Pyrantel Pamoate 3
Fentanyl 2
Midazolam 2
Dexmedetomidine 2
Diazepam 2
Morphine 2
Deracoxib 2
Afoxolaner 2
Spinosad 2

Intestinal stasis Reaction Insights

66 reports name Intestinal stasis; 14 recorded a death outcome (21.2% of reported events, not a population-level mortality rate). VeDDRA code: 1066.

By species: Dog (50 reports), Cat (9 reports), Horse (4 reports). By breed: Domestic Shorthair (7), Retriever - Labrador (6), Crossbred Canine/dog (5).

Most co-reported drugs: Milbemycin Oxime + Spinosad (15 reports), Maropitant Citrate (6 reports), Buprenorphine (5 reports), Isoflurane (5 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.