Reaction profile

The FDA adverse-event record for tablets, abnormal

15,485 FDA adverse-event reports reference tablets, abnormal (VeDDRA 99026). See the species, breeds, and drugs most associated with it below.

15,485
reports citing this reaction
0.1%
death-coded share
Unknown
most-affected species
Ivermectin + Pyrantel As Pamoate Salt
most-associated drug
Verify with FDA CVM →
15,485
Total Reports
11
Deaths
0.1%
Death Rate

Species Most Affected

Unknown 14,863
Dog 561
Cat 50
Human 7
Cattle 1
Horse 1
Sheep 1
Chicken 1

Breeds Most Affected

Unknown 14,877
Dog (unknown) 68
Crossbred Canine/dog 57
Retriever - Labrador 34
Shepherd Dog - German 29
Chihuahua 26
Shih Tzu 25
Retriever - Golden 21
Cat (unknown) 20
Domestic Shorthair 17

Associated Drugs

Ivermectin + Pyrantel As Pamoate Salt 4,498
Afoxolaner 1,742
Carprofen 1,017
Oclacitinib Maleate 642
Ivermectin, Pyrantel 511
Deracoxib 500
Fluralaner Chew Tablets 485
Grapiprant 374
Pimobendan 369
Spinosad 343
Milbemycin Oxime + Spinosad 320
Clomipramine 252
Milbemycin Oxime + Praziquantel 237
Pyrantel Pamoate;Sarolaner 234
Ivermectin/Pyrantel Pamoate Chewable 68Mcg/163Mg 222
Praziquantel 202
Afoxolaner 150Mg / Moxidectin 720Mcg / Pyrantel 300Mg Chewable Tablet 193
Afoxolaner 75Mg / Moxidectin 360Mcg / Pyrantel 150Mg Chewable Tablet 181
Fluralaner 13.64% 12-Week Chew 177
Ivermectin 172

Tablets, Abnormal Reaction Insights

15,485 reports name Tablets, Abnormal; 11 recorded a death outcome (0.1% of reported events, not a population-level mortality rate). VeDDRA code: 99026.

By species: Unknown (14,863 reports), Dog (561 reports), Cat (50 reports). By breed: Unknown (14,877), Dog (unknown) (68), Crossbred Canine/dog (57).

Most co-reported drugs: Ivermectin + Pyrantel As Pamoate Salt (4,498 reports), Afoxolaner (1,742 reports), Carprofen (1,017 reports), Oclacitinib Maleate (642 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.