Reaction profile

The FDA adverse-event record for feeling depressed

33 FDA adverse-event reports reference feeling depressed (VeDDRA 1404). See the species, breeds, and drugs most associated with it below.

33
reports citing this reaction
0.0%
death-coded share
Human
most-affected species
Isoflurane
most-associated drug
Verify with FDA CVM →
33
Total Reports
0
Deaths
0.0%
Death Rate

Species Most Affected

Human 33

Breeds Most Affected

Unknown 33

Associated Drugs

Isoflurane 4
Pyrantel Pamoate 3
Milbemycin 3
Selamectin 3
Moxidectin 2
Eprinomectin 2
Emodepside, Praziquantel 1
Firocoxib 1
Gonadorelin Diacetate Tetrahydrate 1
Imidacloprid, Moxidectin 1
Enrofloxacin 1
Prednisolone, Trimeprazine Tartrate 1
Diclofenac 1
Maropitant 1
Ceftiofur 1
Ivermectin 1
Progesterone 1
Altrenogest 1
Flunixin Meglumine 1
Zilpaterol 1

Feeling depressed Reaction Insights

33 reports name Feeling depressed; 0 recorded a death outcome (0.0% of reported events, not a population-level mortality rate). VeDDRA code: 1404.

By species: Human (33 reports). By breed: Unknown (33).

Most co-reported drugs: Isoflurane (4 reports), Pyrantel Pamoate (3 reports), Milbemycin (3 reports), Selamectin (3 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.