Reaction profile

The FDA adverse-event record for feeling depressed

33 FDA reports name feeling depressed, a lower-volume reaction in the CVM extract (VeDDRA 1404). Plate stamps and neighbourhood peers follow.

#1938 of 2,481
by report volume (all reactions)
33
reports citing this reaction
0.0%
death-coded share
Human
most-affected species
Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Feeling depressed has 33 reports now versus 33 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Feeling depressed changes

FDA AER · VeDDRA plate

Code 1404 VOL-TRACE

VOL-TRACE · DEATH-RARE · LOWER-Q · PHOTO-FINISH · SPECIES-HUMAN · DRUG-LEAD · DESK-NARROW · BOOK-FULL

  • VOL-TRACE 33 reports
  • DEATH-RARE 0.0%
  • LOWER-Q #1938/2481
  • PHOTO-FINISH Abnormal dexamethason…
  • SPECIES-HUMAN Human · 33
  • DRUG-LEAD Isoflurane · 4
  • DESK-NARROW 1 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Abnormal dexamethasone suppression test (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Feeling depressed

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Abnormal dexamethason… · near33Burning mouth sensati… · near33Decreased number of s… · near33Displaced abomasum · near33Feeling depressed · this rea…33Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Feeling depressed

Feeling depressed: low death-coded share in the FDA AER plate

Signature read: Feeling depressed's 0.0% death-coded share is among the lowest in the openFDA reaction corpus. Report volume is lower-third scale: 33 named reports in the openFDA extract. Death-coded share is lower-third: 0 of 33 reports (0.0% of named reports). Nearest volume peer: Abnormal dexamethasone suppression test (±0 reports). Lead species Human (33). Lead co-reported drug Isoflurane (4).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Isoflurane appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Human 33

Breeds Most Affected

Unknown 33

Associated Drugs

Isoflurane 4
Pyrantel Pamoate 3
Milbemycin 3
Selamectin 3
Eprinomectin 2
Moxidectin 2
Emodepside, Praziquantel 1
Firocoxib 1
Gonadorelin Diacetate Tetrahydrate 1
Imidacloprid, Moxidectin 1
Enrofloxacin 1
Prednisolone, Trimeprazine Tartrate 1
Diclofenac 1
Maropitant 1
Progesterone 1
Ceftiofur 1
Ivermectin 1
Altrenogest 1
Flunixin Meglumine 1
Zilpaterol 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Feeling depressed (#1938 of 2,481 by report volume); death-coded 0.0%. PlainBreed reaction plate · death-coded share stamp 0.0% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →