Reaction profile

The FDA adverse-event record for gastroenteritis

834 FDA adverse-event reports reference gastroenteritis (VeDDRA 313). See the species, breeds, and drugs most associated with it below.

834
reports citing this reaction
10.2%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
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834
Total Reports
85
Deaths
10.2%
Death Rate

Species Most Affected

Dog 776
Cat 48
Human 3
Pig 2
Horse 2
Cattle 1
Chicken 1
Lynx 1

Breeds Most Affected

Retriever - Labrador 75
Crossbred Canine/dog 56
Dog (unknown) 37
Terrier - Yorkshire 34
Retriever - Golden 30
Shepherd Dog - German 28
Chihuahua 27
Domestic Shorthair 26
Beagle 24
Shih Tzu 21

Associated Drugs

Milbemycin Oxime + Spinosad 137
Maropitant Citrate 88
Carprofen 74
Oclacitinib Maleate 52
Ivermectin + Pyrantel As Pamoate Salt 45
Trilostane 44
Pyrantel Pamoate;Sarolaner 44
Afoxolaner 41
Milbemycin Oxime + Praziquantel 40
Metronidazole 38
Gabapentin 37
Fluralaner Chew Tablets 34
Moxidectin 33
Spinosad 30
Prednisone 22
Anti-Il31 Mab Mcs Lot #1283563 21
Grapiprant 21
Bedinvetmab 21
Cyclosporine 18
Meloxicam 17

Gastroenteritis Reaction Insights

834 reports name Gastroenteritis; 85 recorded a death outcome (10.2% of reported events, not a population-level mortality rate). VeDDRA code: 313.

By species: Dog (776 reports), Cat (48 reports), Human (3 reports). By breed: Retriever - Labrador (75), Crossbred Canine/dog (56), Dog (unknown) (37).

Most co-reported drugs: Milbemycin Oxime + Spinosad (137 reports), Maropitant Citrate (88 reports), Carprofen (74 reports), Oclacitinib Maleate (52 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.