Reaction profile

The FDA adverse-event record for scrotal irritation nos

Name: Scrotal irritation NOS - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

12 FDA reports name scrotal irritation nos, a lower-volume reaction in the CVM extract (VeDDRA 1737). Plate stamps and neighbourhood peers follow.

#2399 of 2,481
by report volume (all reactions): 12
reports citing this reaction: 8.3%
death-coded share: Dog
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Scrotal irritation NOS has 12 reports now versus 12 in that prior snapshot: 0 the same number of (0.0%).

Report change: +0
Death-coded reports: +0
Death-coded share: +0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

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FDA AER · VeDDRA plate

Code 1737 VOL-TRACE

VOL-TRACE · DEATH-PAR · BOTTOM-DECILE · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

VOL-TRACE 12 reports
DEATH-PAR 8.3%
BOTTOM-DECILE #2399/2481
PHOTO-FINISH Agitated state of mind
SPECIES-DOG Dog · 11
DRUG-LEAD Carprofen · 2
DESK-WIDE 10 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: Agitated state of mind (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Scrotal irritation NOS

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around Scrotal irritation NOS

What the FDA AER plate says about Scrotal irritation NOS

Signature read: 12 reports place Scrotal irritation NOS in the lower third of FDA AER volume (#2399 of 2,481). Report volume is lower-third scale: 12 named reports in the openFDA extract. 1 of 12 reports were death-coded (8.3% of named reports, not a population mortality rate). Nearest volume peer: Agitated state of mind (±0 reports). Lead species Dog (11). Lead co-reported drug Carprofen (2).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Carprofen appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 11

Cat 1

Breeds Most Affected

Retriever - Golden 3

Terrier - Yorkshire 1

Domestic Shorthair 1

Shepherd Dog - Australian 1

Pekingese 1

Shih Tzu 1

Shepherd Dog - German 1

Terrier - Rat 1

Unknown 1

Dachshund - Standard Long-haired 1

Associated Drugs

Carprofen 2

Afoxolaner 2

Ivermectin/Pyrantel Pamoate Chewable 68Mcg/163Mg 1

Fipronil 9.8%/S-Methoprene 8.8%/Cyphenothrin 5.2% Squeeze-On 1

Imidacloprid + Moxidectin 1

Amoxicillin (As Trihydrate); Clavulanate Potassium ( K-Clavulanate) 1

Midazolam Hydrochloride 1

Milbemycin Oxime + Spinosad 1

Cyclosporine 1

Alprazolam 1

Metronidazole 1

Milbemcyin Oxime, Lufenuron, Praziquantel 1

Afoxolaner 68 Mg Chewable Tablets 1

Genta/Momet/Clotrim Ear Oint 1

Milbemycin Oxime + Praziquantel 1

Fluralaner 1

Ivermectin + Pyrantel As Pamoate Salt 1

Melarsomine Dihydrochloride 1

Maropitant Citrate 1

Rabies Virus, 1

What to do with this reaction

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Scrotal irritation NOS (#2399 of 2,481 by report volume); death-coded 8.3%. PlainBreed reaction plate · report volume stamp 12 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →