Reaction profile

The FDA adverse-event record for gastrointestinal foreign body nos

261 FDA adverse-event reports reference gastrointestinal foreign body nos (VeDDRA 2562). See the species, breeds, and drugs most associated with it below.

261
reports citing this reaction
25.3%
death-coded share
Dog
most-affected species
Ivermectin + Pyrantel As Pamoate Salt
most-associated drug
Verify with FDA CVM →
261
Total Reports
66
Deaths
25.3%
Death Rate

Species Most Affected

Dog 238
Cat 16
Cattle 6
Rabbit 1

Breeds Most Affected

Retriever - Labrador 28
Retriever - Golden 21
Crossbred Canine/dog 18
Shepherd Dog - German 8
Chihuahua 7
Domestic Shorthair 7
Pit Bull 6
Collie - Border 6
Dog (unknown) 6
Boxer (German Boxer) 5

Associated Drugs

Ivermectin + Pyrantel As Pamoate Salt 38
Milbemycin Oxime + Praziquantel 33
Maropitant Citrate 30
Fluralaner Chew Tablets 28
Milbemycin Oxime + Spinosad 24
Afoxolaner 22
Carprofen 15
Trilostane 14
Gabapentin 14
Prednisone 12
Lotilaner 8
Fluralaner 13.64% 12-Week Chew 8
Moxidectin 8
Pyrantel Pamoate;Sarolaner 8
Dexmedetomidine 7
Deracoxib 7
Oclacitinib Maleate 6
Metronidazole 6
Grapiprant 6
Fluralaner Spot-On Solution 5

Gastrointestinal foreign body NOS Reaction Insights

261 reports name Gastrointestinal foreign body NOS; 66 recorded a death outcome (25.3% of reported events, not a population-level mortality rate). VeDDRA code: 2562.

By species: Dog (238 reports), Cat (16 reports), Cattle (6 reports). By breed: Retriever - Labrador (28), Retriever - Golden (21), Crossbred Canine/dog (18).

Most co-reported drugs: Ivermectin + Pyrantel As Pamoate Salt (38 reports), Milbemycin Oxime + Praziquantel (33 reports), Maropitant Citrate (30 reports), Fluralaner Chew Tablets (28 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.