Reaction profile

The FDA adverse-event record for incorrect dose administered nos

1,382 FDA reports name incorrect dose administered nos, a high-volume reaction in the CVM extract (VeDDRA 99833). Plate stamps and neighbourhood peers follow.

#306 of 2,481
by report volume (all reactions)
1,382
reports citing this reaction
4.0%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Incorrect dose administered NOS has 1,382 reports now versus 1,374 in that prior snapshot: 8 more (0.6%).

Report change
+8
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Incorrect dose administered NOS changes

FDA AER · VeDDRA plate

Code 99833 VOL-MID

VOL-MID · DEATH-LOW · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 1,382 reports
  • DEATH-LOW 4.0%
  • UPPER-Q #306/2481
  • PHOTO-FINISH Glucosuria
  • SPECIES-DOG Dog · 1,162
  • DRUG-LEAD Milbemycin Oxime… · 186
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Glucosuria (±9 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Incorrect dose administered NOS

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Tarry or black stool… · near1396Decreased red blood c… · near1394Glucosuria · near1391Incorrect dose admini… · thi…1382Pyoderma · near1368Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Incorrect dose administered NOS

Incorrect dose administered NOS: low death-coded share in the FDA AER plate

Signature read: 1,382 reports place Incorrect dose administered NOS in the upper third of FDA AER volume (#306 of 2,481). Report volume is upper-third scale: 1,382 named reports in the openFDA extract. Death-coded share is lower-third: 55 of 1,382 reports (4.0% of named reports). Nearest volume peer: Glucosuria (±9 reports). Lead species Dog (1,162). Lead co-reported drug Milbemycin Oxime + Spinosad (186).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 1,162
Cat 200
Unknown 7
Horse 5
Cattle 4
Turkey 1
Cockatiel 1
Fish 1
Lizard 1

Breeds Most Affected

Domestic Shorthair 109
Crossbred Canine/dog 106
Chihuahua 94
Retriever - Labrador 75
Terrier - Yorkshire 62
Dog (unknown) 46
Retriever - Golden 44
Shih Tzu 43
Spitz - German Pomeranian 33
Maltese 31

Associated Drugs

Milbemycin Oxime + Spinosad 186
Spinosad 183
Genta/Momet/Clotrim Ear Oint 153
Imidacloprid + Moxidectin 100
Ivermectin + Pyrantel As Pamoate Salt 98
Nitenpyram 84
Febantel + Praziquantel + Pyrantel Pamoate 63
Selamectin 57
Orbiflox/Momet/Posaco Eardrops 55
Afoxolaner 34
Fenbendazol Granules 24
Fluralaner Chew Tablets 24
Dexmedetomidine Hydrochloride 22
Trilostane 19
Lufenuron + Milbemycin Oxime 17
Ivermectin 34Mcg, Pyrantel Pamoate 28.5Mg, Praziquantel 28.5Mg 16
Pyrantel Pamoate/Praziquantel 16
Fluralaner 13.64% 12-Week Chew 15
Milbemycin Oxime, Lufenuron 14
Fluralaner Spot-On Solution 14

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Incorrect dose administered NOS, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (4.0% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Incorrect dose administered NOS (#306 of 2,481 by report volume); death-coded 4.0%. PlainBreed reaction plate · report volume stamp 1,382 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →