Reaction profile

The FDA adverse-event record for vocalizing while sleeping

54 FDA reports name vocalizing while sleeping, a lower-volume reaction in the CVM extract (VeDDRA 2505). Plate stamps and neighbourhood peers follow.

#1702 of 2,481
by report volume (all reactions)
54
reports citing this reaction
14.8%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Vocalizing while sleeping has 54 reports now versus 52 in that prior snapshot: 2 more (3.8%).

Report change
+2
Death-coded reports
+0
Death-coded share
−0.6 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Vocalizing while sleeping changes

FDA AER · VeDDRA plate

Code 2505 VOL-LOW

VOL-LOW · DEATH-ELEV · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 54 reports
  • DEATH-ELEV 14.8%
  • MID-PACK #1702/2481
  • PHOTO-FINISH Acute mastitis
  • SPECIES-DOG Dog · 47
  • DRUG-LEAD Afoxolaner · 6
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Acute mastitis (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Vocalizing while sleeping

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Acute mastitis · near54Arthropathy NOS · near54Exophthalmia · near54Hypovolaemic shock · near54Vocalizing while slee… · thi…54Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Vocalizing while sleeping

What the FDA AER plate says about Vocalizing while sleeping

Signature read: 54 reports place Vocalizing while sleeping in the lower third of FDA AER volume (#1702 of 2,481). Report volume is lower-third scale: 54 named reports in the openFDA extract. 8 of 54 reports were death-coded (14.8% of named reports, not a population mortality rate). Nearest volume peer: Acute mastitis (±0 reports). Lead species Dog (47). Lead co-reported drug Afoxolaner (6).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Afoxolaner appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 47
Cat 7

Breeds Most Affected

Shih Tzu 5
Retriever - Golden 5
Crossbred Canine/dog 5
Chihuahua 4
Retriever - Labrador 3
Maltese 3
Shepherd Dog - German 3
Domestic Shorthair 3
Pit Bull 2
Terrier - Yorkshire 2

Associated Drugs

Afoxolaner 6
Buprenorphine 4
Ivermectin + Pyrantel As Pamoate Salt 4
Fluralaner 13.64% 12-Week Chew 4
Fluralaner Chew Tablets 3
Oclacitinib Maleate 3
Sarolaner 3
Milbemycin Oxime + Spinosad 3
Moxidectin 3
Pimobendan 2
Furosemide 2
Ketamine 2
Midazolam Hydrochloride 2
Isoflurane 2
Selamectin;Sarolaner 2
Imidacloprid + Moxidectin 2
Doxycycline 2
Milbemycin/Lufenuron Tablets 2
Nitenpyram 2
Pyrantel Pamoate;Sarolaner 2

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Vocalizing while sleeping, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (54 here).

Similar death-coded share

Nearest other reactions by death-coded share (14.8% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Vocalizing while sleeping (#1702 of 2,481 by report volume); death-coded 14.8%. PlainBreed reaction plate · report volume stamp 54 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →