Reaction profile

The FDA adverse-event record for paralysis nos

332 FDA adverse-event reports reference paralysis nos (VeDDRA 1677). See the species, breeds, and drugs most associated with it below.

332
reports citing this reaction
46.7%
death-coded share
Dog
most-affected species
Bedinvetmab
most-associated drug
Verify with FDA CVM →
332
Total Reports
155
Deaths
46.7%
Death Rate

Species Most Affected

Dog 282
Cat 39
Cattle 3
Horse 3
Turkey 3
Pig 1
Rabbit 1

Breeds Most Affected

Retriever - Labrador 26
Dog (unknown) 26
Domestic Shorthair 23
Retriever - Golden 19
Shepherd Dog - German 18
Crossbred Canine/dog 16
Chihuahua 14
Siberian Husky 8
Shih Tzu 7
Spitz - German Pomeranian 7

Associated Drugs

Bedinvetmab 86
Milbemycin Oxime + Spinosad 37
Carprofen 34
Pyrantel Pamoate;Sarolaner 21
Afoxolaner 19
Gabapentin 16
Maropitant Citrate 12
Cefovecin 11
Sarolaner 11
Spinosad 10
Oclacitinib Maleate 10
Prednisone 9
Fluralaner 13.64% 12-Week Chew 9
Nitenpyram 8
Fluralaner Chew Tablets 8
Frunevetmab 8
Metronidazole 7
Selamectin 6
Grapiprant 6
Ivermectin 5

Paralysis NOS Reaction Insights

332 reports name Paralysis NOS; 155 recorded a death outcome (46.7% of reported events, not a population-level mortality rate). VeDDRA code: 1677.

By species: Dog (282 reports), Cat (39 reports), Cattle (3 reports). By breed: Retriever - Labrador (26), Dog (unknown) (26), Domestic Shorthair (23).

Most co-reported drugs: Bedinvetmab (86 reports), Milbemycin Oxime + Spinosad (37 reports), Carprofen (34 reports), Pyrantel Pamoate;Sarolaner (21 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.