Reaction profile

The FDA adverse-event record for falling

4,310 FDA adverse-event reports reference falling (VeDDRA 651). See the species, breeds, and drugs most associated with it below.

4,310
reports citing this reaction
16.0%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
Verify with FDA CVM →
4,310
Total Reports
688
Deaths
16.0%
Death Rate

Species Most Affected

Dog 3,559
Cat 664
Horse 53
Cattle 17
Human 6
Rabbit 4
Goat 1
Pig 1
Sheep 1
Other Equids 1

Breeds Most Affected

Domestic Shorthair 406
Retriever - Labrador 327
Crossbred Canine/dog 295
Chihuahua 192
Terrier - Yorkshire 184
Retriever - Golden 150
Shepherd Dog - German 133
Shih Tzu 130
Boxer (German Boxer) 105
Shepherd Dog - Australian 93

Associated Drugs

Milbemycin Oxime + Spinosad 413
Bedinvetmab 393
Afoxolaner 388
Fluralaner 13.64% 12-Week Chew 250
Sarolaner 244
Carprofen 241
Pyrantel Pamoate;Sarolaner 209
Ivermectin + Pyrantel As Pamoate Salt 206
Fluralaner Chew Tablets 205
Gabapentin 189
Maropitant Citrate 162
Spinosad 140
Trilostane 135
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 121
Prednisone 106
Oclacitinib Maleate 106
Moxidectin 104
Milbemycin Oxime + Praziquantel 100
Selamectin 96
Cefovecin 95

Falling Reaction Insights

4,310 reports name Falling; 688 recorded a death outcome (16.0% of reported events, not a population-level mortality rate). VeDDRA code: 651.

By species: Dog (3,559 reports), Cat (664 reports), Horse (53 reports). By breed: Domestic Shorthair (406), Retriever - Labrador (327), Crossbred Canine/dog (295).

Most co-reported drugs: Milbemycin Oxime + Spinosad (413 reports), Bedinvetmab (393 reports), Afoxolaner (388 reports), Fluralaner 13.64% 12-Week Chew (250 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.