Reaction profile

The FDA adverse-event record for desquamation

62 FDA adverse-event reports reference desquamation (VeDDRA 942). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1631 of 2,481
by report volume (all reactions)
62
reports citing this reaction
8.1%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Desquamation has 62 reports now versus 62 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Desquamation changes

FDA AER · VeDDRA plate

Code 942 VOL-LOW

VOL-LOW · DEATH-PAR · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 62 reports
  • DEATH-PAR 8.1%
  • MID-PACK #1631/2481
  • PHOTO-FINISH Application site ting…
  • SPECIES-DOG Dog · 40
  • DRUG-LEAD Imidacloprid + Mo… · 15
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Application site tingling (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Desquamation

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Application site ting… · near62Claw / hoof / nail lo… · near62Desquamation · this reaction62Dropper, Abnormal · near62Eyesight trouble · near62Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Desquamation

What the FDA AER plate says about Desquamation

Signature read: 5 death-coded reports is a thin tail count for Desquamation in the CVM extract. Report volume sits in the middle third of the reaction corpus. 5 of 62 reports were death-coded (8.1% of named reports, not a population mortality rate). Nearest volume peer: Application site tingling (±0 reports). Lead species Dog (40). Lead co-reported drug Imidacloprid + Moxidectin (15).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Imidacloprid + Moxidectin appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 40
Cat 13
Horse 8
Goat 1

Breeds Most Affected

Domestic Shorthair 7
Retriever - Labrador 4
Crossbred Canine/dog 4
Quarter Horse 3
Terrier - Boston 3
Retriever - Golden 3
Terrier - Yorkshire 2
Mastiff 2
Spitz - German Pomeranian 2
Chihuahua 2

Associated Drugs

Imidacloprid + Moxidectin 15
Emodepside + Praziquantel 5
Prednisone 4
Lufenuron + Milbemycin Oxime 3
Ivermectin/Pyrantel Pamoate Chewable 272Mcg/652Mg 3
Ivermectin(1.55%)/Praziquantel(7.75%) Paste 3
Isoflurane 3
Enrofloxacin 2
Fipronil 10%/S Methoprene 9% Spot On 2
Cefovecin 2
Flumethrin-Imidacloprid 2
Florfenicol/Terbinafine Hydrochloride/Mometasone Furoate 2
Ivermectin + Pyrantel As Pamoate Salt 2
Afoxolaner 2
Grapiprant 2
Metronidazole 2
Gabapentin 2
Butorphanol 2
Ivermectin + Praziquantel 2
Fluralaner 13.64% 12-Week Chew 2

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Desquamation, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (62 here).

Similar death-coded share

Nearest other reactions by death-coded share (8.1% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Desquamation (#1631 of 2,481 by report volume); death-coded 8.1%. PlainBreed reaction plate · death-coded report count stamp 5 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →