Reaction profile

The FDA adverse-event record for inappropriate elimination nos

222 FDA adverse-event reports reference inappropriate elimination nos (VeDDRA 2674). See the species, breeds, and drugs most associated with it below.

222
reports citing this reaction
28.4%
death-coded share
Dog
most-affected species
Bedinvetmab
most-associated drug
Verify with FDA CVM →
222
Total Reports
63
Deaths
28.4%
Death Rate

Species Most Affected

Dog 173
Cat 48
Rabbit 1

Breeds Most Affected

Domestic Shorthair 34
Retriever - Labrador 15
Dog (unknown) 15
Shepherd Dog - German 11
Crossbred Canine/dog 8
Retriever - Golden 7
Terrier - Boston 6
Domestic Longhair 5
Spaniel (unspecified) 5
Beagle 5

Associated Drugs

Bedinvetmab 81
Gabapentin 29
Pyrantel Pamoate;Sarolaner 23
Carprofen 19
Trilostane 18
Maropitant Citrate 16
Frunevetmab 14
Sarolaner 9
Cefovecin 8
Afoxolaner 7
Prednisone 7
Enrofloxacin 6
Grapiprant 6
Selamectin;Sarolaner 5
Moxidectin 5
Anti-Il31 Mab Mcs Lot #1283563 5
Diphenhydramine 5
Galliprant 5
Leptospira Canicola L-15 Strain C-51;Leptospira Grippotyphosa 1550 Lot 10005 Str 5
Ivermectin + Pyrantel As Pamoate Salt 4

Inappropriate elimination NOS Reaction Insights

222 reports name Inappropriate elimination NOS; 63 recorded a death outcome (28.4% of reported events, not a population-level mortality rate). VeDDRA code: 2674.

By species: Dog (173 reports), Cat (48 reports), Rabbit (1 reports). By breed: Domestic Shorthair (34), Retriever - Labrador (15), Dog (unknown) (15).

Most co-reported drugs: Bedinvetmab (81 reports), Gabapentin (29 reports), Pyrantel Pamoate;Sarolaner (23 reports), Carprofen (19 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.