Reaction profile

The FDA adverse-event record for pr-duodenum, lesion(s)

26 FDA adverse-event reports reference pr-duodenum, lesion(s) (VeDDRA 99674). See the species, breeds, and drugs most associated with it below.

26
reports citing this reaction
57.7%
death-coded share
Dog
most-affected species
Maropitant Citrate
most-associated drug
Verify with FDA CVM →
26
Total Reports
15
Deaths
57.7%
Death Rate

Species Most Affected

Dog 23
Cat 2
Other 1

Breeds Most Affected

Retriever - Labrador 4
Crossbred Canine/dog 1
Terrier - Yorkshire 1
Boxer (German Boxer) 1
Retriever - Golden 1
Shar Pei 1
Pointing Dog - German Short-haired 1
Bulldog 1
Doberman Pinscher 1
Norwegian Forest 1

Associated Drugs

Maropitant Citrate 5
Metronidazole 4
Famotidine 3
Tramadol 3
Carprofen 3
Grapiprant 3
Firocoxib 227 Mg Chewable 2
Enrofloxacin 2
Ampicillin 2
Prednisolone 2
Sucralfate 2
Metoclopramide 2
Oclacitinib Maleate 2
Deracoxib 2
Fluralaner Chew Tablets 2
Meloxicam 2
Milbemycin Oxime + Praziquantel 2
Amoxicillin Trihydrate; Clavulanate Potassium ( K-Clavulanate) 1
Canine Adenovirus Type 2, Strain Manhattan, 12-13-76; Canine Coronavirus, Strain 1
Ivermectin 1

PR-DUODENUM, LESION(S) Reaction Insights

26 reports name PR-DUODENUM, LESION(S); 15 recorded a death outcome (57.7% of reported events, not a population-level mortality rate). VeDDRA code: 99674.

By species: Dog (23 reports), Cat (2 reports), Other (1 reports). By breed: Retriever - Labrador (4), Crossbred Canine/dog (1), Terrier - Yorkshire (1).

Most co-reported drugs: Maropitant Citrate (5 reports), Metronidazole (4 reports), Famotidine (3 reports), Tramadol (3 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.