Reaction profile

The FDA adverse-event record for ear flapping/twitching

72 FDA adverse-event reports reference ear flapping/twitching (VeDDRA 1986). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1553 of 2,481
by report volume (all reactions)
72
reports citing this reaction
0.0%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Ear flapping/twitching has 72 reports now versus 71 in that prior snapshot: 1 more (1.4%).

Report change
+1
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Ear flapping/twitching changes

FDA AER · VeDDRA plate

Code 1986 VOL-LOW

VOL-LOW · DEATH-RARE · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 72 reports
  • DEATH-RARE 0.0%
  • MID-PACK #1553/2481
  • PHOTO-FINISH Elevated BUN
  • SPECIES-DOG Dog · 46
  • DRUG-LEAD Milbemycin Oxime… · 6
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Elevated BUN (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Ear flapping/twitching

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Ear flapping/twitching · thi…72Elevated BUN · near72Embolism · near72Fatty liver · near72IGA Animal mortality… · near72Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Ear flapping/twitching

Ear flapping/twitching: low death-coded share in the FDA AER plate

Signature read: Ear flapping/twitching's 0.0% death-coded share is among the lowest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is lower-third: 0 of 72 reports (0.0% of named reports). Nearest volume peer: Elevated BUN (±0 reports). Lead species Dog (46). Lead co-reported drug Milbemycin Oxime + Spinosad (6).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 46
Cat 24
Horse 2

Breeds Most Affected

Domestic Shorthair 12
Retriever - Golden 7
Pit Bull 5
Crossbred Canine/dog 4
Retriever - Labrador 4
Domestic Longhair 4
Dachshund (unspecified) 2
Boxer (German Boxer) 2
Terrier - Cairn 2
Cat (other) 2

Associated Drugs

Milbemycin Oxime + Spinosad 6
Afoxolaner 6
Spinosad 5
Ivermectin + Pyrantel As Pamoate Salt 5
Selamectin 4
Nitenpyram 4
Fluralaner 13.64% 12-Week Chew 4
Selamectin;Sarolaner 4
Mirtazapine 3
Maropitant 2
Cefovecin 2
Ivermectin, Pyrantel 2
Meloxicam 2
Fluralaner Chew Tablets 2
Ivermectin / Pyrantel Tablets 2
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 2
Emodepside + Praziquantel 2
Eprinomectin + Esafoxolaner + Praziquantel 2
Dexamethasone 1
Antibiotic (Unknown) 1

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Ear flapping/twitching, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (72 here).

Similar death-coded share

Nearest other reactions by death-coded share (0.0% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Ear flapping/twitching (#1553 of 2,481 by report volume); death-coded 0.0%. PlainBreed reaction plate · death-coded share stamp 0.0% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →