Reaction profile

The FDA adverse-event record for heart block 1st degree

15 FDA reports name heart block 1st degree, a lower-volume reaction in the CVM extract (VeDDRA 2431). Plate stamps and neighbourhood peers follow.

#2301 of 2,481
by report volume (all reactions)
15
reports citing this reaction
13.3%
death-coded share
Dog
most-affected species
Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Heart block 1st degree has 15 reports now versus 15 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Heart block 1st degree changes

FDA AER · VeDDRA plate

Code 2431 VOL-TRACE

VOL-TRACE · DEATH-ELEV · BOTTOM-DECILE · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 15 reports
  • DEATH-ELEV 13.3%
  • BOTTOM-DECILE #2301/2481
  • PHOTO-FINISH Abomasal ulcer
  • SPECIES-DOG Dog · 15
  • DRUG-LEAD Propofol · 5
  • DESK-WIDE 12 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Abomasal ulcer (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Heart block 1st degree

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Abomasal ulcer · near15Burning sensation of… · near15Chronic hepatitis · near15Conjunctival haemorrh… · near15Heart block 1st degree · thi…15Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Heart block 1st degree

What the FDA AER plate says about Heart block 1st degree

Signature read: 15 reports place Heart block 1st degree in the lower third of FDA AER volume (#2301 of 2,481). Report volume is lower-third scale: 15 named reports in the openFDA extract. 2 of 15 reports were death-coded (13.3% of named reports, not a population mortality rate). Nearest volume peer: Abomasal ulcer (±0 reports). Lead species Dog (15). Lead co-reported drug Propofol (5).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Propofol appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 15

Breeds Most Affected

Shih Tzu 2
Retriever - Golden 2
Retriever - Labrador 2
Dog (unknown) 1
Terrier - Bull - American Pit 1
Schnauzer (unspecified) 1
Collie - Border 1
Lhasa Apso 1
Shepherd Dog - German 1
Dachshund - Miniature 1

Associated Drugs

Propofol 5
Dexmedetomidine Hydrochloride 5
Butorphanol 4
Anesthetic 3
Carprofen 2
Hydromorphone Hcl 2
Isoflurane 2
Atipamezole Hydrochloride 2
Atropine 2
Meloxicam 2
Bedinvetmab 2
Pyrantel Pamoate;Sarolaner 2
Acepromazine Maleate 1
Sevoflurane 1
Canine Influenza Virus H3N8;Canine Influenza Virus H3N2 1
Polysulfated Glycosaminoglycan 1
Lufenuron + Milbemycin Oxime + Praziquantel 1
Diazepam 1
Cefazolin 1
Cefovecin 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Heart block 1st degree (#2301 of 2,481 by report volume); death-coded 13.3%. PlainBreed reaction plate · report volume stamp 15 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →