Reaction profile

The FDA adverse-event record for hair modification nos

382 FDA reports name hair modification nos, a high-volume reaction in the CVM extract (VeDDRA 1508). Plate stamps and neighbourhood peers follow.

#752 of 2,481
by report volume (all reactions)
382
reports citing this reaction
5.2%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Hair modification NOS has 382 reports now versus 380 in that prior snapshot: 2 more (0.5%).

Report change
+2
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Hair modification NOS changes

FDA AER · VeDDRA plate

Code 1508 VOL-LOW

VOL-LOW · DEATH-PAR · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 382 reports
  • DEATH-PAR 5.2%
  • MID-PACK #752/2481
  • PHOTO-FINISH Proprioception loss
  • SPECIES-DOG Dog · 253
  • DRUG-LEAD Imidacloprid + Mo… · 35
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Proprioception loss (±0 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Hair modification NOS

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Disorder of red blood… · near383Hair modification NOS · this…382Proprioception loss · near382Stroke · near382Alopecia general · near381Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Hair modification NOS

Hair modification NOS: low death-coded share in the FDA AER plate

Signature read: Hair modification NOS's 5.2% death-coded share is among the lowest in the openFDA reaction corpus. Report volume is upper-third scale: 382 named reports in the openFDA extract. Death-coded share is lower-third: 20 of 382 reports (5.2% of named reports). Nearest volume peer: Proprioception loss (±0 reports). Lead species Dog (253). Lead co-reported drug Imidacloprid + Moxidectin (35).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Imidacloprid + Moxidectin appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 253
Cat 70
Cattle 39
Horse 14
Human 4
Sheep 1
Pig 1

Breeds Most Affected

Retriever - Labrador 27
Domestic Shorthair 27
Retriever - Golden 23
Crossbred Canine/dog 19
Domestic (unspecified) 18
Dog (unknown) 15
Shepherd Dog - German 9
Aberdeen Angus 8
Cattle (unknown) 8
Chihuahua 8

Associated Drugs

Imidacloprid + Moxidectin 35
Afoxolaner 30
Selamectin 26
Trilostane 23
Cyclosporine 22
Oclacitinib Maleate 19
Cyclosporine A 18
Prednisone 17
Spinosad 15
Desoxycorticosterone Pivalate 12
Milbemycin Oxime + Spinosad 12
Ivermectin + Pyrantel As Pamoate Salt 12
Pergolide Mesylate 10
Emodepside + Praziquantel 10
Carprofen 8
Eprinomectin 5% Injection 8
Nitenpyram 7
Imidacloprid, Moxidectin 6
Enrofloxacin 6
Monensin Sodium 6

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Hair modification NOS, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (382 here).

Similar death-coded share

Nearest other reactions by death-coded share (5.2% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Hair modification NOS (#752 of 2,481 by report volume); death-coded 5.2%. PlainBreed reaction plate · death-coded share stamp 5.2% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →