Reaction profile

The FDA adverse-event record for injection site sarcoma

102 FDA adverse-event reports reference injection site sarcoma (VeDDRA 101). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1385 of 2,481
by report volume (all reactions)
102
reports citing this reaction
18.6%
death-coded share
Cat
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Injection site sarcoma has 102 reports now versus 92 in that prior snapshot: 10 more (10.9%).

Report change
+10
Death-coded reports
+0
Death-coded share
−2.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Injection site sarcoma changes

FDA AER · VeDDRA plate

Code 101 VOL-LOW

VOL-LOW · DEATH-ELEV · MID-PACK · PHOTO-FINISH · SPECIES-CAT · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 102 reports
  • DEATH-ELEV 18.6%
  • MID-PACK #1385/2481
  • PHOTO-FINISH Agglutination test, p…
  • SPECIES-CAT Cat · 88
  • DRUG-LEAD Robenacoxib · 43
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Agglutination test, positive (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Injection site sarcoma

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Agglutination test, p… · near102Difficulty chewing · near102Facial rash (For urti… · near102Injection site sarcoma · thi…102PR-BRAIN, LESION(S) · near102Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Injection site sarcoma

What the FDA AER plate says about Injection site sarcoma

Signature read: death-coded share at 18.6% is the most distinctive outcome stamp on Injection site sarcoma. Report volume sits in the middle third of the reaction corpus. 19 of 102 reports were death-coded (18.6% of named reports, not a population mortality rate). Nearest volume peer: Agglutination test, positive (±0 reports). Lead species Cat (88). Lead co-reported drug Robenacoxib (43).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Robenacoxib appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Cat 88
Dog 14

Breeds Most Affected

Domestic Shorthair 63
Domestic Longhair 9
Domestic Mediumhair 6
Siamese 3
Shih Tzu 3
Retriever - Labrador 3
Bengal 2
Ocicat 1
Himalayan 1
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 1

Associated Drugs

Robenacoxib 43
Buprenorphine 27
Cefovecin 26
Maropitant Citrate 21
Rabies Vaccine 20
Gabapentin 18
Butorphanol 13
Propofol 13
Rabies Vaccine, Killed Virus 12
Cefovecin Sodium 12
Frunevetmab 11
Dexmedetomidine 10
Rabies Virus, High Cell Passage-Street Alabama Dufferin Strain 10
Midazolam 9
Meloxicam 8
Fluid Therapy 8
Rabies Virus, Kv 7
Fvrcp Vaccine 7
Feline Leukemia Vaccine, Killed Virus 7
Isoflurane 7

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Injection site sarcoma, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (18.6% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Injection site sarcoma (#1385 of 2,481 by report volume); death-coded 18.6%. PlainBreed reaction plate · death-coded share stamp 18.6% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →