Reaction profile

The FDA adverse-event record for blood in vomit

2,656 FDA adverse-event reports reference blood in vomit (VeDDRA 343). See the species, breeds, and drugs most associated with it below.

2,656
reports citing this reaction
19.3%
death-coded share
Dog
most-affected species
Carprofen
most-associated drug
Verify with FDA CVM →
2,656
Total Reports
512
Deaths
19.3%
Death Rate

Species Most Affected

Dog 2,369
Cat 285
Human 2

Breeds Most Affected

Retriever - Labrador 309
Crossbred Canine/dog 196
Domestic Shorthair 153
Shepherd Dog - German 108
Terrier - Yorkshire 98
Retriever - Golden 85
Dog (unknown) 79
Chihuahua 76
Shih Tzu 68
Boxer (German Boxer) 51

Associated Drugs

Carprofen 380
Moxidectin 211
Maropitant Citrate 192
Milbemycin Oxime + Spinosad 152
Afoxolaner 114
Grapiprant 107
Deracoxib 98
Meloxicam 98
Pyrantel Pamoate;Sarolaner 98
Gabapentin 95
Spinosad 88
Fluralaner Chew Tablets 87
Oclacitinib Maleate 85
Ivermectin + Pyrantel As Pamoate Salt 84
Milbemycin Oxime + Praziquantel 65
Firocoxib 63
Famotidine 62
Melarsomine Dihydrochloride 59
Sucralfate 59
Sarolaner 59

Blood in vomit Reaction Insights

2,656 reports name Blood in vomit; 512 recorded a death outcome (19.3% of reported events, not a population-level mortality rate). VeDDRA code: 343.

By species: Dog (2,369 reports), Cat (285 reports), Human (2 reports). By breed: Retriever - Labrador (309), Crossbred Canine/dog (196), Domestic Shorthair (153).

Most co-reported drugs: Carprofen (380 reports), Moxidectin (211 reports), Maropitant Citrate (192 reports), Milbemycin Oxime + Spinosad (152 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.