Reaction profile

The FDA adverse-event record for blood in vomit

2,751 FDA reports name blood in vomit, a high-volume reaction in the CVM extract (VeDDRA 343). Plate stamps and neighbourhood peers follow.

#168 of 2,481
by report volume (all reactions)
2,751
reports citing this reaction
18.9%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Blood in vomit has 2,751 reports now versus 2,704 in that prior snapshot: 47 more (1.7%).

Report change
+47
Death-coded reports
+3
Death-coded share
−0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Blood in vomit changes

FDA AER · VeDDRA plate

Code 343 VOL-MID

VOL-MID · DEATH-ELEV · TOP-DECILE · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 2,751 reports
  • DEATH-ELEV 18.9%
  • TOP-DECILE #168/2481
  • PHOTO-FINISH Lack of efficacy (rou…
  • SPECIES-DOG Dog · 2,447
  • DRUG-LEAD Carprofen · 388
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Lack of efficacy (roundworm) (±14 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Blood in vomit

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Lack of efficacy (rou… · near2765Blood in vomit · this reacti…2751Device Defective NOS · near2733Hypothermia · near2724Urticaria · near2718Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Blood in vomit

What the FDA AER plate says about Blood in vomit

Signature read: 519 death-coded reports is a heavy tail count for Blood in vomit in the CVM extract. Report volume is upper-third scale: 2,751 named reports in the openFDA extract. 519 of 2,751 reports were death-coded (18.9% of named reports, not a population mortality rate). Nearest volume peer: Lack of efficacy (roundworm) (±14 reports). Lead species Dog (2,447). Lead co-reported drug Carprofen (388).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Carprofen appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 2,447
Cat 302
Human 2

Breeds Most Affected

Retriever - Labrador 313
Crossbred Canine/dog 205
Domestic Shorthair 165
Shepherd Dog - German 111
Terrier - Yorkshire 101
Retriever - Golden 91
Dog (unknown) 81
Chihuahua 79
Shih Tzu 69
Shepherd Dog - Australian 52

Associated Drugs

Carprofen 388
Moxidectin 223
Maropitant Citrate 209
Milbemycin Oxime + Spinosad 152
Afoxolaner 118
Grapiprant 108
Pyrantel Pamoate;Sarolaner 108
Gabapentin 103
Meloxicam 100
Deracoxib 98
Oclacitinib Maleate 90
Spinosad 88
Ivermectin + Pyrantel As Pamoate Salt 88
Fluralaner Chew Tablets 87
Famotidine 66
Milbemycin Oxime + Praziquantel 66
Firocoxib 64
Sucralfate 63
Melarsomine Dihydrochloride 62
Sarolaner 61

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Blood in vomit, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (2,751 here).

Similar death-coded share

Nearest other reactions by death-coded share (18.9% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Blood in vomit (#168 of 2,481 by report volume); death-coded 18.9%. PlainBreed reaction plate · death-coded report count stamp 519 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →