Reaction profile

The FDA adverse-event record for chronic hepatitis

15 FDA reports name chronic hepatitis, a lower-volume reaction in the CVM extract (VeDDRA 2763). Plate stamps and neighbourhood peers follow.

#2294 of 2,481
by report volume (all reactions)
15
reports citing this reaction
26.7%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Chronic hepatitis has 15 reports now versus 15 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Chronic hepatitis changes

FDA AER · VeDDRA plate

Code 2763 VOL-TRACE

VOL-TRACE · DEATH-HOT · BOTTOM-DECILE · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 15 reports
  • DEATH-HOT 26.7%
  • BOTTOM-DECILE #2294/2481
  • PHOTO-FINISH Abomasal ulcer
  • SPECIES-DOG Dog · 12
  • DRUG-LEAD Ivermectin + Pyra… · 5
  • DESK-WIDE 14 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Abomasal ulcer (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Chronic hepatitis

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Abomasal ulcer · near15Burning sensation of… · near15Chronic hepatitis · this rea…15Conjunctival haemorrh… · near15Devitalisation · near15Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Chronic hepatitis

Chronic hepatitis: high death-coded share in the FDA AER plate

Signature read: 15 reports place Chronic hepatitis in the lower third of FDA AER volume (#2294 of 2,481). Report volume is lower-third scale: 15 named reports in the openFDA extract. Death-coded share is upper-third: 4 of 15 reports (26.7% of named reports). Nearest volume peer: Abomasal ulcer (±0 reports). Lead species Dog (12). Lead co-reported drug Ivermectin + Pyrantel As Pamoate Salt (5).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 12
Horse 2
Cat 1

Breeds Most Affected

Shepherd Dog - German 2
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 1
Pointing Dog - German Short-haired 1
Bulldog 1
Chihuahua 1
Retriever - Labrador 1
Newfoundland 1
Bulldog - English 1
Domestic Mediumhair 1
Paint 1

Associated Drugs

Ivermectin + Pyrantel As Pamoate Salt 5
Carprofen 4
Trilostane 2
Bedinvetmab 2
Afoxolaner 2
Pyrantel Pamoate;Sarolaner 1
Oclacitinib 1
Cefalexin 1
Milbemycin Oxime + Praziquantel 1
Lotilaner 1
Ivermectin 1
Oclacitinib Maleate 1
Omega-3 Fatty Acids 1
Moxidetin + Pyrantal + Sarolaner 1
Sarolaner 1
Pimobendan 1
Moxidectin 1
Fluralaner Spot-On Solution 1
Firocoxib 1
Ponazuril 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Chronic hepatitis (#2294 of 2,481 by report volume); death-coded 26.7%. PlainBreed reaction plate · report volume stamp 15 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →