Reaction profile

The FDA adverse-event record for chronic hepatitis

14 FDA adverse-event reports reference chronic hepatitis (VeDDRA 2763). See the species, breeds, and drugs most associated with it below.

14
reports citing this reaction
28.6%
death-coded share
Dog
most-affected species
Ivermectin + Pyrantel As Pamoate Salt
most-associated drug
Verify with FDA CVM →
14
Total Reports
4
Deaths
28.6%
Death Rate

Species Most Affected

Dog 11
Horse 2
Cat 1

Breeds Most Affected

Shepherd Dog - German 2
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 1
Pointing Dog - German Short-haired 1
Bulldog 1
Chihuahua 1
Retriever - Labrador 1
Newfoundland 1
Bulldog - English 1
Domestic Mediumhair 1
Paint 1

Associated Drugs

Ivermectin + Pyrantel As Pamoate Salt 5
Carprofen 4
Trilostane 2
Bedinvetmab 2
Afoxolaner 2
Pyrantel Pamoate;Sarolaner 1
Oclacitinib 1
Cefalexin 1
Milbemycin Oxime + Praziquantel 1
Lotilaner 1
Ivermectin 1
Oclacitinib Maleate 1
Omega-3 Fatty Acids 1
Moxidetin + Pyrantal + Sarolaner 1
Sarolaner 1
Pimobendan 1
Moxidectin 1
Fluralaner Spot-On Solution 1
Firocoxib 1
Ponazuril 1

Chronic hepatitis Reaction Insights

14 reports name Chronic hepatitis; 4 recorded a death outcome (28.6% of reported events, not a population-level mortality rate). VeDDRA code: 2763.

By species: Dog (11 reports), Horse (2 reports), Cat (1 reports). By breed: Shepherd Dog - German (2), Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) (1), Pointing Dog - German Short-haired (1).

Most co-reported drugs: Ivermectin + Pyrantel As Pamoate Salt (5 reports), Carprofen (4 reports), Trilostane (2 reports), Bedinvetmab (2 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.