Uncoded sign
VeDDRA Code: 1216
10,171 adverse event reports referencing this reaction
10,171
Total Reports
219
Deaths
220.0%
Death Rate
Species Most Affected
Unknown 8,768
Dog 1,123
Cat 99
Horse 73
Human 47
Cattle 41
Pig 9
Chicken 7
Other Canids 1
Turkey 1
Breeds Most Affected
Unknown 8,819
Retriever - Labrador 95
Crossbred Canine/dog 71
Domestic Shorthair 65
Dog (unknown) 65
Chihuahua 55
Boxer (German Boxer) 43
Dachshund (unspecified) 38
Terrier - Yorkshire 37
Shih Tzu 34
Associated Drugs
Milbemycin Oxime + Spinosad 1,480
Ivermectin + Pyrantel As Pamoate Salt 486
Enrofloxacin 481
Imidacloprid + Moxidectin 478
Spinosad 453
Cyclosporine A 392
Trilostane 309
Fluralaner Chew Tablets 283
Hydrocortisone Aceponate/Miconazole Nitrate/Gentamicin Sulfate 281
Selamectin 237
Afoxolaner 237
Moxidectin 231
Clomipramine 209
Melarsomine Dihydrochloride Injection 195
Meloxicam 193
Carprofen 168
Cyclosporin Ointment 146
Deracoxib 131
Ivermectin(1%)/Clorsulon(10%) Injection 123
Tresaderm Dermatological Solution 118
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.