Reaction profile

The FDA adverse-event record for histiocytoma

262 FDA adverse-event reports reference histiocytoma (VeDDRA 917). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#917 of 2,481
by report volume (all reactions)
262
reports citing this reaction
5.3%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Histiocytoma has 262 reports now versus 257 in that prior snapshot: 5 more (1.9%).

Report change
+5
Death-coded reports
+0
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Histiocytoma changes

FDA AER · VeDDRA plate

Code 917 VOL-LOW

VOL-LOW · DEATH-PAR · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 262 reports
  • DEATH-PAR 5.3%
  • MID-PACK #917/2481
  • PHOTO-FINISH Attention-seeking beh…
  • SPECIES-DOG Dog · 259
  • DRUG-LEAD Oclacitinib Malea… · 203
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Attention-seeking behaviour (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Histiocytoma

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Hyperaemic mucous mem… · near263Impaired vocalisation · near263Licking at injection… · near263Attention-seeking beh… · near262Histiocytoma · this reaction262Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Histiocytoma

Histiocytoma: low death-coded share in the FDA AER plate

Signature read: Histiocytoma's 5.3% death-coded share is among the lowest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is lower-third: 14 of 262 reports (5.3% of named reports). Nearest volume peer: Attention-seeking behaviour (±0 reports). Lead species Dog (259). Lead co-reported drug Oclacitinib Maleate (203).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Oclacitinib Maleate appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 259
Pig 2
Cat 1

Breeds Most Affected

Retriever - Labrador 30
Boxer (German Boxer) 24
Terrier - Bull - American Pit 19
Dog (unknown) 14
Bulldog - French 11
Crossbred Canine/dog 11
Terrier - Yorkshire 9
Beagle 8
Retriever - Golden 6
Shepherd Dog - German 6

Associated Drugs

Oclacitinib Maleate 203
Anti-Il31 Mab Mcs Lot #1283563 25
Milbemycin Oxime + Spinosad 19
Cyclosporine A 11
Ketoconazole 11
Ilunocitinib 10
Cefpodoxime 8
Prednisolone; Trimeprazine Tartrate 8
Selamectin 8
Cephalexin 8
Milbemycin Oxime + Praziquantel 8
Prednisone 7
Ivermectin 7
Immunotherapy 7
Lotilaner 7
Cefovecin 5
Fish Oil 5
Afoxolaner 5
Cyclosporine 5
Diphenhydramine Hcl 4

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Histiocytoma, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (5.3% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Histiocytoma (#917 of 2,481 by report volume); death-coded 5.3%. PlainBreed reaction plate · death-coded share stamp 5.3% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →