NT - renal infarcts

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VeDDRA Code: 2366

16 adverse event reports referencing this reaction

16
Total Reports
13
Deaths
8120.0%
Death Rate

Species Most Affected

Dog 12
Cat 3
Cattle 1

Breeds Most Affected

Retriever - Golden 2
Retriever - Labrador 1
Schnauzer - Miniature 1
Boxer (German Boxer) 1
Holstein-Friesian also known as Holstein 1
Terrier - Yorkshire 1
Domestic Mediumhair 1
Shepherd (unspecified) 1
Chihuahua 1
Cat (unknown) 1

Associated Drugs

Grapiprant 3
Carprofen 2
Cetirizine 2
Lufenuron + Milbemycin Oxime 1
Spinosad 1
Fluralaner Chew Tablets 1
Ceftiofur Sodium 1
Insulin 1
Fish Oil 1
Tramadol 1
Glucosamine & Chondroitin Sulfate 1
Levothyroxine Sodium 1
Fluralaner 1
Fluralaner Spot-On Solution 1
Moxidectin 1
Dexamethasone 1
Butorphanol Injectable 1
Fluralaner 13.64% 12-Week Chew 1
Cefovecin 1
Selamectin;Sarolaner 1

Data Summary

Metric Value
Total reports referencing reaction 16
Reports with fatal outcome 13
Case-fatality rate (reported events) 8120.0%
Species observed 3
Breeds observed 15
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 2366.

NT - renal infarcts Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 16 adverse event reports that reference NT - renal infarcts as a reaction term, including 13 reports with a death outcome — a 8120.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 2366, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

NT - renal infarcts appears most frequently in reports for Dog (12 reports), Cat (3 reports), Cattle (1 reports) — with Dog dominating at 12 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Golden (2), Retriever - Labrador (1), Schnauzer - Miniature (1). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with NT - renal infarcts are Grapiprant (3 reports), Carprofen (2 reports), Cetirizine (2 reports), Lufenuron + Milbemycin Oxime (1 reports), with Grapiprant appearing alongside this reaction in 3 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial