Reduced growth rate

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VeDDRA Code: 2188

42 adverse event reports referencing this reaction

42
Total Reports
18
Deaths
4290.0%
Death Rate

Species Most Affected

Dog 15
Cattle 13
Pig 8
Cat 3
Chicken 2
Goat 1

Breeds Most Affected

Crossbred Porcine/Pig 6
Cattle (unknown) 5
Cattle (other) 4
Domestic Shorthair 3
Shepherd Dog - German 2
Shepherd Dog - Australian 2
Dog (unknown) 2
Aberdeen Angus 2
Bulldog - French 2
Catahoula Leopard Dog 1

Associated Drugs

Monensin Sodium 8
Narasin 6
Milbemycin Oxime + Spinosad 4
Cefovecin 4
Tulathromycin 3
Clostr Perf*2/Clos Others*4 Kb 3
Tiamulin 2
Estradiol + Trenbolone Acetate + Tylosin Tartrate 2
Trenbolone; Estradiol; Tylosin Tartrate 2
Pyrantel Pamoate;Sarolaner 2
Milbemycin Oxime + Praziquantel 2
Trenbolone Acet/Estradiol Impl 2
Fenbendazol Suspension 2
Florfenicol/Flunixin Inj-Triac 2
Bovine Virus*5/Past M+Mh Lv/Lb 2
Doramectin 1
Decoquinate 1
Bovine Parainfluenza Virus 3, Reisinger(Nl-Bk-6), Mlv; Bovine Respiratory Syncyt 1
Clostridium Chauvoei, Strain F, Lot No. 2-84; Clostridium Novyi, 8296, Kb; Clost 1
Phenylpropanolamine Hcl 1

Data Summary

Metric Value
Total reports referencing reaction 42
Reports with fatal outcome 18
Case-fatality rate (reported events) 4290.0%
Species observed 6
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 2188.

Reduced growth rate Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 42 adverse event reports that reference Reduced growth rate as a reaction term, including 18 reports with a death outcome — a 4290.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 2188, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Reduced growth rate appears most frequently in reports for Dog (15 reports), Cattle (13 reports), Pig (8 reports) — with Dog dominating at 15 entries. Within those species, the breeds most often named alongside this reaction are Crossbred Porcine/Pig (6), Cattle (unknown) (5), Cattle (other) (4). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Reduced growth rate are Monensin Sodium (8 reports), Narasin (6 reports), Milbemycin Oxime + Spinosad (4 reports), Cefovecin (4 reports), with Monensin Sodium appearing alongside this reaction in 8 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial