Reaction profile

The FDA adverse-event record for milk drop

53 FDA adverse-event reports reference milk drop (VeDDRA 534). See the species, breeds, and drugs most associated with it below.

53
reports citing this reaction
32.1%
death-coded share
Cattle
most-affected species
Monensin Sodium
most-associated drug
Verify with FDA CVM →
53
Total Reports
17
Deaths
32.1%
Death Rate

Species Most Affected

Cattle 48
Dog 3
Pig 2

Breeds Most Affected

Holstein-Friesian also known as Holstein 27
Jersey 8
Cattle (unknown) 6
Mixed (Cattle) 3
Hereford cattle 1
Cattle (unspecified) 1
Cattle (other) 1
Terrier - Yorkshire 1
Commercial hybrid 1
Hound - Basset 1

Associated Drugs

Monensin Sodium 35
Dinoprost Tromethamine 6
Sometribove 3
Sometribove Zinc Suspension 1
Ceftiofur Hydrochloride 1
Moxidectin 1
Bovine Parainfluenza Virus 3, Reisinger(Nl-Bk-6), Mlv; Bovine Respiratory Syncyt 1
Milbemycin Oxime + Spinosad 1
5-Way Vaccine (Unknown) 1
Ceftiofur Crystalline Free Acid 1
Eprinomectin 5 Mg/Ml Pour-On Solution 1
Fenbendazol Powder Mix 1
Oclacitinib Maleate 1
Pegbovigrastim 1
Fluralaner Chew Tablets 1
Canine B Burgdorferi *2 Alu Kb 1
Bovine Rhinotracheitis + Virus Diarrhea + Parainfluenza + Respiratory Syncytial Virus Vaccine + Mannheimia Haemolytica Toxoid 1
Autogenous Bacterin 1
Tilmicosin 1
Gonadorelin Hydrochloride 1

Milk drop Reaction Insights

53 reports name Milk drop; 17 recorded a death outcome (32.1% of reported events, not a population-level mortality rate). VeDDRA code: 534.

By species: Cattle (48 reports), Dog (3 reports), Pig (2 reports). By breed: Holstein-Friesian also known as Holstein (27), Jersey (8), Cattle (unknown) (6).

Most co-reported drugs: Monensin Sodium (35 reports), Dinoprost Tromethamine (6 reports), Sometribove (3 reports), Sometribove Zinc Suspension (1 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.