Reaction profile

The FDA adverse-event record for milk drop

Name: Milk drop - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

54 FDA reports name milk drop, a lower-volume reaction in the CVM extract (VeDDRA 534). Plate stamps and neighbourhood peers follow.

#1701 of 2,481
by report volume (all reactions): 54
reports citing this reaction: 31.5%
death-coded share: Cattle
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Milk drop has 54 reports now versus 53 in that prior snapshot: 1 more (1.9%).

Report change: +1
Death-coded reports: +0
Death-coded share: −0.6 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Milk drop changes

FDA AER · VeDDRA plate

Code 534 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-CATTLE · DRUG-LEAD · DESK-WIDE · BOOK-FULL

VOL-LOW 54 reports
DEATH-HOT 31.5%
MID-PACK #1701/2481
PHOTO-FINISH Acute mastitis
SPECIES-CATTLE Cattle · 49
DRUG-LEAD Monensin Sodium · 36
DESK-WIDE 13 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: Acute mastitis (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Milk drop

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around Milk drop

Milk drop: high death-coded share in the FDA AER plate

Signature read: Milk drop's 31.5% death-coded share is among the highest in the openFDA reaction corpus. Report volume is lower-third scale: 54 named reports in the openFDA extract. Death-coded share is upper-third: 17 of 54 reports (31.5% of named reports). Nearest volume peer: Acute mastitis (±0 reports). Lead species Cattle (49). Lead co-reported drug Monensin Sodium (36).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Cattle 49

Dog 3

Pig 2

Breeds Most Affected

Holstein-Friesian also known as Holstein 28

Jersey 8

Cattle (unknown) 6

Mixed (Cattle) 3

Hereford cattle 1

Cattle (unspecified) 1

Cattle (other) 1

Terrier - Yorkshire 1

Commercial hybrid 1

Hound - Basset 1

Associated Drugs

Monensin Sodium 36

Dinoprost Tromethamine 6

Sometribove 3

Sometribove Zinc Suspension 1

Moxidectin 1

Ceftiofur Hydrochloride 1

Bovine Parainfluenza Virus 3, Reisinger(Nl-Bk-6), Mlv; Bovine Respiratory Syncyt 1

Milbemycin Oxime + Spinosad 1

5-Way Vaccine (Unknown) 1

Eprinomectin 5 Mg/Ml Pour-On Solution 1

Ceftiofur Crystalline Free Acid 1

Fenbendazol Powder Mix 1

Oclacitinib Maleate 1

Pegbovigrastim 1

Fluralaner Chew Tablets 1

Canine B Burgdorferi *2 Alu Kb 1

Bovine Rhinotracheitis + Virus Diarrhea + Parainfluenza + Respiratory Syncytial Virus Vaccine + Mannheimia Haemolytica Toxoid 1

Autogenous Bacterin 1

Tilmicosin 1

Gonadorelin Hydrochloride 1

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Milk drop, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (54 here).

Acute mastitis 54 Arthropathy NOS 54 Exophthalmia 54 Hypovolaemic shock 54

Similar death-coded share

Nearest other reactions by death-coded share (31.5% here), distinct from the volume row.

Acid-base disorder 31.5% Melaena 31.5% Mammary gland neoplasm NOS 31.5% Unconscious 31.5%

What to do with this reaction

Compare Milk drop's report profile against similar reactions nationwide. See similar reactions
Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Milk drop (#1701 of 2,481 by report volume); death-coded 31.5%. PlainBreed reaction plate · death-coded share stamp 31.5% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →