Reaction profile

The FDA adverse-event record for insert, abnormal

Name: Insert, Abnormal - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://creativecommons.org/publicdomain/zero/1.0/

55 FDA adverse-event reports reference insert, abnormal (VeDDRA 99975). See the species, breeds, and drugs most associated with it below.

55
reports citing this reaction: 1.8%
death-coded share: Unknown
most-affected species: Progesterone
most-associated drug

Compiled by PlainBreed Editorial, Pet Health Editorial Team

Verify with FDA CVM →

Total Reports

Deaths

1.8%

Death Rate

Species Most Affected

Unknown 47

Cattle 6

White tailed deer 1

Cat 1

Breeds Most Affected

Unknown 48

Aberdeen Angus 3

Cattle (unknown) 1

Cattle (unspecified) 1

Domestic Shorthair 1

Mixed (Cattle) 1

Associated Drugs

Progesterone 36

Ivermectin 2

Ivermectin + Pyrantel 2

Capromorelin Tartrate 2

Doramectin 1

Bovine Viral Diarrhea Virus, 53637, Bvd2Mlv-D; Bovine Viral Diarrhea Virus, Nadl 1

Maropitant Citrate 1

Dimethyl Sulfoxide; Fluocinolone Acetonide 1

Bovine Coronavirus, St Lot 28, 10-17-83, Hansen Isolate; Bovine Rotavirus, Lot 0 1

Chlorhexidine Diacetate 1

Ivermectin + Pyrantel As Pamoate Salt 1

Meloxicam 1

Polysulfated Glycosaminoglycan 1

Milbemycin Oxime + Spinosad 1

Nitenpyram 1

Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 1

Emodepside + Praziquantel 1

Lotilaner 1

Amoxicillin Trihydrate;Clavulanate Potassium ( K-Clavulanate) 1

Hyaluronic Acid 1

Insert, Abnormal Reaction Insights

55 reports name Insert, Abnormal; 1 recorded a death outcome (1.8% of reported events, not a population-level mortality rate). VeDDRA code: 99975.

By species: Unknown (47 reports), Cattle (6 reports), White tailed deer (1 reports). By breed: Unknown (48), Aberdeen Angus (3), Cattle (unknown) (1).

Most co-reported drugs: Progesterone (36 reports), Ivermectin (2 reports), Ivermectin + Pyrantel (2 reports), Capromorelin Tartrate (2 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.