Reaction profile

The FDA adverse-event record for prolonged bleeding nos

179 FDA adverse-event reports reference prolonged bleeding nos (VeDDRA 151). See the species, breeds, and drugs most associated with it below.

179
reports citing this reaction
31.8%
death-coded share
Dog
most-affected species
Carprofen
most-associated drug
Verify with FDA CVM →
179
Total Reports
57
Deaths
31.8%
Death Rate

Species Most Affected

Dog 148
Cat 27
Human 2
Cattle 1
Horse 1

Breeds Most Affected

Retriever - Labrador 21
Domestic Shorthair 17
Terrier - Bull - American Pit 9
Boxer (German Boxer) 8
Shepherd Dog - German 8
Shih Tzu 6
Schnauzer (unspecified) 5
Pug 5
Dachshund (unspecified) 5
Cat (unknown) 5

Associated Drugs

Carprofen 31
Milbemycin Oxime + Spinosad 20
Oclacitinib Maleate 15
Maropitant Citrate 14
Meloxicam 12
Polysulfated Glycosaminoglycan 12
Gabapentin 10
Moxidectin 10
Cyclosporine 10
Prednisone 9
Pyrantel Pamoate;Sarolaner 9
Ketamine 8
Milbemycin Oxime + Praziquantel 8
Diazepam 7
Robenacoxib 7
Metronidazole 7
Dexamethasone 7
Famotidine 7
Selamectin 7
Cefovecin 7

Prolonged bleeding NOS Reaction Insights

179 reports name Prolonged bleeding NOS; 57 recorded a death outcome (31.8% of reported events, not a population-level mortality rate). VeDDRA code: 151.

By species: Dog (148 reports), Cat (27 reports), Human (2 reports). By breed: Retriever - Labrador (21), Domestic Shorthair (17), Terrier - Bull - American Pit (9).

Most co-reported drugs: Carprofen (31 reports), Milbemycin Oxime + Spinosad (20 reports), Oclacitinib Maleate (15 reports), Maropitant Citrate (14 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.