Reaction profile

The FDA adverse-event record for salivary gland disorder

60 FDA reports name salivary gland disorder, a lower-volume reaction in the CVM extract (VeDDRA 2383). Plate stamps and neighbourhood peers follow.

#1654 of 2,481
by report volume (all reactions)
60
reports citing this reaction
10.0%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Salivary gland disorder has 60 reports now versus 58 in that prior snapshot: 2 more (3.4%).

Report change
+2
Death-coded reports
+0
Death-coded share
−0.3 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Salivary gland disorder changes

FDA AER · VeDDRA plate

Code 2383 VOL-LOW

VOL-LOW · DEATH-ELEV · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 60 reports
  • DEATH-ELEV 10.0%
  • MID-PACK #1654/2481
  • PHOTO-FINISH Foam in the trachea
  • SPECIES-DOG Dog · 56
  • DRUG-LEAD Trilostane · 18
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Foam in the trachea (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Salivary gland disorder

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Foam in the trachea · near60Heavy sweating · near60Salivary gland disord… · thi…60Skin thinning · near60Transient blindness · near60Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Salivary gland disorder

What the FDA AER plate says about Salivary gland disorder

Signature read: 6 death-coded reports is a thin tail count for Salivary gland disorder in the CVM extract. Report volume is lower-third scale: 60 named reports in the openFDA extract. 6 of 60 reports were death-coded (10.0% of named reports, not a population mortality rate). Nearest volume peer: Foam in the trachea (±0 reports). Lead species Dog (56). Lead co-reported drug Trilostane (18).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Trilostane appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 56
Human 2
Cat 2

Breeds Most Affected

Terrier - Boston 5
Chihuahua 5
Dachshund - Miniature 4
Retriever - Labrador 4
Maltese 3
Unknown 3
Bulldog - French 3
Shepherd Dog - German 3
Dachshund (unspecified) 2
Boxer (German Boxer) 2

Associated Drugs

Trilostane 18
Oclacitinib Maleate 8
Carprofen 6
Anti-Il31 Mab Mcs Lot #1283563 5
Milbemycin Oxime + Spinosad 4
Moxidectin 4
Famotidine 4
Maropitant Citrate 4
Prednisone 3
Capromorelin Tartrate 3
Fluralaner 13.64% 12-Week Chew 3
Buprenorphine 3
Hydroxyzine 2
Fluralaner Chew Tablets 2
Milbemycin Oxime + Praziquantel 2
Amoxicillin Trihydrate;Clavulanate Potassium ( K-Clavulanate) 2
Diphenhydramine Hcl 2
Metronidazole 2
Tylosin Tartrate 2
Enrofloxacin 2

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Salivary gland disorder, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (60 here).

Similar death-coded share

Nearest other reactions by death-coded share (10.0% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Salivary gland disorder (#1654 of 2,481 by report volume); death-coded 10.0%. PlainBreed reaction plate · death-coded report count stamp 6 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →