Reaction profile

The FDA adverse-event record for asphyxia

15 FDA adverse-event reports reference asphyxia (VeDDRA 1916). See the species, breeds, and drugs most associated with it below.

15
reports citing this reaction
60.0%
death-coded share
Dog
most-affected species
Device: Animal Care (Bowls, Crates, Etc)
most-associated drug
Verify with FDA CVM →
15
Total Reports
9
Deaths
60.0%
Death Rate

Species Most Affected

Dog 9
Cat 5
Horse 1

Breeds Most Affected

Dog (unknown) 4
Domestic Shorthair 3
Pekingese 1
Quarter Horse 1
Mountain Dog - Bernese 1
Retriever - Golden 1
Beagle 1
Unknown 1
Chihuahua 1
Cat (unknown) 1

Associated Drugs

Device: Animal Care (Bowls, Crates, Etc) 2
Afoxolaner 2
Isoflurane 2
Milbemycin Oxime + Spinosad 2
Detomidine 1
Ivermectin 1
Deracoxib 1
Milbemycin Oxime + Praziquantel 1
Spinosad 1
Ivermectin + Pyrantel As Pamoate Salt 1
Fluralaner Spot-On Solution 1
Cannabidiol 1
Anti-Seizure Medication (Unknown) 1
Buprenorphine 1
Dexmedetomidine 1
Ketamine 1
Butorphanol 1
Maropitant Citrate 1
Fluralaner 13.64% 12-Week Chew 1
Praziquantel 1

Asphyxia Reaction Insights

15 reports name Asphyxia; 9 recorded a death outcome (60.0% of reported events, not a population-level mortality rate). VeDDRA code: 1916.

By species: Dog (9 reports), Cat (5 reports), Horse (1 reports). By breed: Dog (unknown) (4), Domestic Shorthair (3), Pekingese (1).

Most co-reported drugs: Device: Animal Care (Bowls, Crates, Etc) (2 reports), Afoxolaner (2 reports), Isoflurane (2 reports), Milbemycin Oxime + Spinosad (2 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.