Reaction profile

The FDA adverse-event record for hypoxia

171 FDA adverse-event reports reference hypoxia (VeDDRA 2186). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1119 of 2,481
by report volume (all reactions)
171
reports citing this reaction
34.5%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Hypoxia has 171 reports now versus 170 in that prior snapshot: 1 more (0.6%).

Report change
+1
Death-coded reports
+1
Death-coded share
+0.4 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Hypoxia changes

FDA AER · VeDDRA plate

Code 2186 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 171 reports
  • DEATH-HOT 34.5%
  • MID-PACK #1119/2481
  • PHOTO-FINISH Abrasion
  • SPECIES-DOG Dog · 108
  • DRUG-LEAD Isoflurane · 29
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Abrasion (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Report-volume neighbourhood around Hypoxia

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Abrasion · near171Hypoxia · this reaction171Myositis · near171Piloerection · near171Defecation related to… · near170Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Hypoxia

Hypoxia: high death-coded share in the FDA AER plate

Signature read: Hypoxia's 34.5% death-coded share is among the highest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is upper-third: 59 of 171 reports (34.5% of named reports). Nearest volume peer: Abrasion (±0 reports). Lead species Dog (108). Lead co-reported drug Isoflurane (29).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 108
Cat 44
Horse 7
Other Rodents 2
Mouse 2
Goat 2
Chicken 1
Unknown 1
Cattle 1
Other Bovine 1

Breeds Most Affected

Domestic Shorthair 26
Retriever - Labrador 11
Crossbred Canine/dog 7
Dog (unknown) 7
Spitz - German Pomeranian 6
Terrier - Yorkshire 6
Chihuahua 6
Collie - Border 5
Unknown 5
Beagle 5

Associated Drugs

Isoflurane 29
Maropitant Citrate 21
Buprenorphine 15
Dexmedetomidine Hydrochloride 14
Midazolam 13
Butorphanol 13
Propofol 12
Carprofen 11
Ketamine 10
Moxidectin 10
Sevoflurane 10
Alfaxalone 9
Atipamezole Hydrochloride 8
Melarsomine Dihydrochloride 8
Meloxicam 7
Ketamine Hydrochloride 7
Gabapentin 7
Diazepam 7
Atropine 7
Pyrantel Pamoate;Sarolaner 7

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Hypoxia, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (171 here).

Similar death-coded share

Nearest other reactions by death-coded share (34.5% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Hypoxia (#1119 of 2,481 by report volume); death-coded 34.5%. PlainBreed reaction plate · death-coded share stamp 34.5% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →