Reaction profile

The FDA adverse-event record for myasthenia gravis

37 FDA reports name myasthenia gravis, a lower-volume reaction in the CVM extract (VeDDRA 1142). Plate stamps and neighbourhood peers follow.

#1898 of 2,481
by report volume (all reactions)
37
reports citing this reaction
24.3%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Myasthenia gravis has 37 reports now versus 37 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Myasthenia gravis changes

FDA AER · VeDDRA plate

Code 1142 VOL-TRACE

VOL-TRACE · DEATH-HOT · LOWER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 37 reports
  • DEATH-HOT 24.3%
  • LOWER-Q #1898/2481
  • PHOTO-FINISH Blistering of mouth
  • SPECIES-DOG Dog · 33
  • DRUG-LEAD Maropitant Citrate · 9
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Blistering of mouth (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Myasthenia gravis

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Blistering of mouth · near37CARBON DIOXIDE HIGH,… · near37Cartilage degeneration · near37Cleft palate · near37Myasthenia gravis · this rea…37Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Myasthenia gravis

Myasthenia gravis: high death-coded share in the FDA AER plate

Signature read: 37 reports place Myasthenia gravis in the lower third of FDA AER volume (#1898 of 2,481). Report volume is lower-third scale: 37 named reports in the openFDA extract. Death-coded share is upper-third: 9 of 37 reports (24.3% of named reports). Nearest volume peer: Blistering of mouth (±0 reports). Lead species Dog (33). Lead co-reported drug Maropitant Citrate (9).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 33
Cat 4

Breeds Most Affected

Shepherd Dog - German 4
Retriever - Labrador 4
Crossbred Canine/dog 4
Boxer (German Boxer) 3
Siamese 2
Beagle 2
Domestic Shorthair 2
Spaniel - King Charles Cavalier 1
Chihuahua 1
Pointing Dog - German Short-haired 1

Associated Drugs

Maropitant Citrate 9
Bedinvetmab 7
Carprofen 4
Pyrantel Pamoate;Sarolaner 4
Moxidectin 3
Trilostane 3
Fluralaner 13.64% 12-Week Chew 3
Milbemycin Oxime + Spinosad 2
Oclacitinib Maleate 2
Sucralfate 2
Methocarbamol 2
Thiamazole 2
Afoxolaner 2
Fluralaner Chew Tablets 2
Famotidine 2
Frunevetmab 2
Spinosad 1
Ceftiofur Sodium 1
Propofol 1
Isoflurane 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Myasthenia gravis (#1898 of 2,481 by report volume); death-coded 24.3%. PlainBreed reaction plate · report volume stamp 37 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →