Reaction profile

The FDA adverse-event record for myasthenia gravis

36 FDA adverse-event reports reference myasthenia gravis (VeDDRA 1142). See the species, breeds, and drugs most associated with it below.

36
reports citing this reaction
25.0%
death-coded share
Dog
most-affected species
Maropitant Citrate
most-associated drug
Verify with FDA CVM →
36
Total Reports
9
Deaths
25.0%
Death Rate

Species Most Affected

Dog 32
Cat 4

Breeds Most Affected

Shepherd Dog - German 4
Retriever - Labrador 4
Crossbred Canine/dog 4
Boxer (German Boxer) 3
Siamese 2
Beagle 2
Domestic Shorthair 2
Spaniel - King Charles Cavalier 1
Chihuahua 1
Pointing Dog - German Short-haired 1

Associated Drugs

Maropitant Citrate 8
Bedinvetmab 6
Carprofen 4
Pyrantel Pamoate;Sarolaner 4
Moxidectin 3
Trilostane 3
Fluralaner 13.64% 12-Week Chew 3
Milbemycin Oxime + Spinosad 2
Oclacitinib Maleate 2
Sucralfate 2
Methocarbamol 2
Thiamazole 2
Afoxolaner 2
Famotidine 2
Fluralaner Chew Tablets 2
Frunevetmab 2
Spinosad 1
Ceftiofur Sodium 1
Propofol 1
Isoflurane 1

Myasthenia gravis Reaction Insights

36 reports name Myasthenia gravis; 9 recorded a death outcome (25.0% of reported events, not a population-level mortality rate). VeDDRA code: 1142.

By species: Dog (32 reports), Cat (4 reports). By breed: Shepherd Dog - German (4), Retriever - Labrador (4), Crossbred Canine/dog (4).

Most co-reported drugs: Maropitant Citrate (8 reports), Bedinvetmab (6 reports), Carprofen (4 reports), Pyrantel Pamoate;Sarolaner (4 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.