Vestibular disorder NOS

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VeDDRA Code: 373

1,383 adverse event reports referencing this reaction

1,383
Total Reports
191
Deaths
1380.0%
Death Rate

Species Most Affected

Dog 1,138
Cat 239
Rabbit 5
Horse 1

Breeds Most Affected

Domestic Shorthair 141
Retriever - Labrador 137
Crossbred Canine/dog 93
Shepherd Dog - German 51
Dog (unknown) 48
Retriever - Golden 47
Chihuahua 38
Shepherd Dog - Australian 37
Shih Tzu 37
Collie - Border 36

Associated Drugs

Bedinvetmab 302
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 227
Carprofen 126
Maropitant Citrate 110
Gabapentin 101
Milbemycin Oxime + Spinosad 63
Trilostane 51
Prednisone 44
Afoxolaner 41
Oclacitinib Maleate 40
Meclizine 37
Pyrantel Pamoate;Sarolaner 36
Spinosad 35
Grapiprant 35
Enrofloxacin 33
Florfenicol/Terbinafine Hydrochloride/Mometasone Furoate 32
Fluralaner 13.64% 12-Week Chew 30
Cefovecin Sodium 28
Sarolaner 28
Cefovecin 26

Data Summary

Metric Value
Total reports referencing reaction 1,383
Reports with fatal outcome 191
Case-fatality rate (reported events) 1380.0%
Species observed 4
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 373.

Vestibular disorder NOS Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 1,383 adverse event reports that reference Vestibular disorder NOS as a reaction term, including 191 reports with a death outcome — a 1380.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 373, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Vestibular disorder NOS appears most frequently in reports for Dog (1,138 reports), Cat (239 reports), Rabbit (5 reports) — with Dog dominating at 1,138 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (141), Retriever - Labrador (137), Crossbred Canine/dog (93). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Vestibular disorder NOS are Bedinvetmab (302 reports), Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride (227 reports), Carprofen (126 reports), Maropitant Citrate (110 reports), with Bedinvetmab appearing alongside this reaction in 302 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial