Reaction profile

The FDA adverse-event record for scale

321 FDA adverse-event reports reference scale (VeDDRA 1196). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#842 of 2,481
by report volume (all reactions)
321
reports citing this reaction
5.0%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Scale has 321 reports now versus 312 in that prior snapshot: 9 more (2.9%).

Report change
+9
Death-coded reports
+2
Death-coded share
+0.5 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Scale changes

FDA AER · VeDDRA plate

Code 1196 VOL-LOW

VOL-LOW · DEATH-LOW · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 321 reports
  • DEATH-LOW 5.0%
  • MID-PACK #842/2481
  • PHOTO-FINISH Impaired hearing
  • SPECIES-DOG Dog · 242
  • DRUG-LEAD Milbemycin Oxime… · 28
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Impaired hearing (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Scale

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Deafness NOS · near324Implant, Abnormal · near322Impaired hearing · near321Scale · this reaction321Injection site hair l… · near318Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Scale

Scale: low death-coded share in the FDA AER plate

Signature read: Scale's 5.0% death-coded share is among the lowest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is lower-third: 16 of 321 reports (5.0% of named reports). Nearest volume peer: Impaired hearing (±0 reports). Lead species Dog (242). Lead co-reported drug Milbemycin Oxime + Spinosad (28).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 242
Cat 67
Cattle 6
Horse 4
Human 2

Breeds Most Affected

Domestic Shorthair 34
Retriever - Labrador 32
Crossbred Canine/dog 20
Shih Tzu 13
Retriever - Golden 10
Chihuahua 10
Domestic (unspecified) 9
Maltese 9
Dachshund (unspecified) 7
Shepherd Dog - German 7

Associated Drugs

Milbemycin Oxime + Spinosad 28
Oclacitinib Maleate 27
Afoxolaner 23
Selamectin 21
Carprofen 18
Trilostane 17
Prednisone 16
Bedinvetmab 16
Spinosad 14
Gabapentin 14
Cyclosporine 13
Cefovecin 13
Ivermectin + Pyrantel As Pamoate Salt 12
Anti-Il31 Mab Mcs Lot #1283563 12
Frunevetmab 11
Cefovecin Sodium 10
Fluralaner Chew Tablets 10
Imidacloprid + Moxidectin 9
Maropitant Citrate 9
Fipronil 9.8%/S-Methoprene 8.8%/ Amitraz 22.1% Spot-On 8

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Scale, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (321 here).

Similar death-coded share

Nearest other reactions by death-coded share (5.0% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Scale (#842 of 2,481 by report volume); death-coded 5.0%. PlainBreed reaction plate · death-coded share stamp 5.0% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →