Reaction profile

The FDA adverse-event record for confused

387 FDA adverse-event reports reference confused (VeDDRA 1393). See the species, breeds, and drugs most associated with it below.

387
reports citing this reaction
7.5%
death-coded share
Dog
most-affected species
Afoxolaner
most-associated drug
Verify with FDA CVM →
387
Total Reports
29
Deaths
7.5%
Death Rate

Species Most Affected

Dog 329
Cat 35
Human 21
Horse 2

Breeds Most Affected

Retriever - Golden 27
Retriever - Labrador 25
Crossbred Canine/dog 23
Chihuahua 22
Unknown 21
Domestic Shorthair 19
Shepherd Dog - German 13
Terrier - Yorkshire 12
Dog (unknown) 12
Boxer (German Boxer) 11

Associated Drugs

Afoxolaner 49
Milbemycin Oxime + Spinosad 42
Fluralaner Chew Tablets 34
Sarolaner 26
Ivermectin + Pyrantel As Pamoate Salt 25
Fluralaner 13.64% 12-Week Chew 24
Trilostane 23
Carprofen 19
Milbemycin Oxime + Praziquantel 16
Oclacitinib Maleate 14
Moxidectin 14
Maropitant Citrate 13
Fluralaner Spot-On Solution 12
Pyrantel Pamoate;Sarolaner 10
Selamectin 9
Ivermectin 8
Spinosad 7
Imidacloprid + Moxidectin 7
Cefovecin 6
Diazepam 6

Confused Reaction Insights

387 reports name Confused; 29 recorded a death outcome (7.5% of reported events, not a population-level mortality rate). VeDDRA code: 1393.

By species: Dog (329 reports), Cat (35 reports), Human (21 reports). By breed: Retriever - Golden (27), Retriever - Labrador (25), Crossbred Canine/dog (23).

Most co-reported drugs: Afoxolaner (49 reports), Milbemycin Oxime + Spinosad (42 reports), Fluralaner Chew Tablets (34 reports), Sarolaner (26 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.