Reaction profile

The FDA adverse-event record for skin sore

1,538 FDA adverse-event reports reference skin sore (VeDDRA 962). See the species, breeds, and drugs most associated with it below.

1,538
reports citing this reaction
5.3%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
Verify with FDA CVM →
1,538
Total Reports
82
Deaths
5.3%
Death Rate

Species Most Affected

Dog 1,146
Cat 353
Horse 15
Human 12
Cattle 6
Pig 3
Ferret 2
Donkey 1

Breeds Most Affected

Domestic Shorthair 214
Retriever - Labrador 133
Crossbred Canine/dog 80
Shepherd Dog - German 62
Dog (unknown) 56
Retriever - Golden 55
Shih Tzu 48
Terrier - Yorkshire 47
Chihuahua 47
Pit Bull 37

Associated Drugs

Milbemycin Oxime + Spinosad 193
Frunevetmab 129
Afoxolaner 109
Spinosad 96
Selamectin 88
Imidacloprid + Moxidectin 83
Bedinvetmab 71
Fluralaner Chew Tablets 65
Oclacitinib Maleate 65
Nitenpyram 54
Carprofen 54
Fluralaner 13.64% 12-Week Chew 51
Gabapentin 48
Ivermectin + Pyrantel As Pamoate Salt 42
Cefovecin 38
Trilostane 37
Milbemycin Oxime + Praziquantel 34
Pyrantel Pamoate;Sarolaner 33
Prednisone 30
Fluralaner Spot-On Solution 28

Skin sore Reaction Insights

1,538 reports name Skin sore; 82 recorded a death outcome (5.3% of reported events, not a population-level mortality rate). VeDDRA code: 962.

By species: Dog (1,146 reports), Cat (353 reports), Horse (15 reports). By breed: Domestic Shorthair (214), Retriever - Labrador (133), Crossbred Canine/dog (80).

Most co-reported drugs: Milbemycin Oxime + Spinosad (193 reports), Frunevetmab (129 reports), Afoxolaner (109 reports), Spinosad (96 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.