Reaction profile

The FDA adverse-event record for chronic kidney disease

30 FDA reports name chronic kidney disease, a lower-volume reaction in the CVM extract (VeDDRA 3213). Plate stamps and neighbourhood peers follow.

#1993 of 2,481
by report volume (all reactions)
30
reports citing this reaction
20.0%
death-coded share
Cat
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Chronic kidney disease has 30 reports now versus 16 in that prior snapshot: 14 more (87.5%).

Report change
+14
Death-coded reports
+0
Death-coded share
−17.5 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Chronic kidney disease changes

FDA AER · VeDDRA plate

Code 3213 VOL-TRACE

VOL-TRACE · DEATH-HOT · LOWER-Q · PHOTO-FINISH · SPECIES-CAT · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 30 reports
  • DEATH-HOT 20.0%
  • LOWER-Q #1993/2481
  • PHOTO-FINISH Abnormal spermatozoa…
  • SPECIES-CAT Cat · 20
  • DRUG-LEAD Bedinvetmab · 5
  • DESK-WIDE 12 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Abnormal spermatozoa NOS (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Chronic kidney disease

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Abnormal spermatozoa… · near30Atelectasis · near30Bone marrow suppressi… · near30Chronic kidney disease · thi…30Congenital musculo-sk… · near30Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Chronic kidney disease

What the FDA AER plate says about Chronic kidney disease

Signature read: 30 reports place Chronic kidney disease in the lower third of FDA AER volume (#1993 of 2,481). Report volume is lower-third scale: 30 named reports in the openFDA extract. 6 of 30 reports were death-coded (20.0% of named reports, not a population mortality rate). Nearest volume peer: Abnormal spermatozoa NOS (±0 reports). Lead species Cat (20). Lead co-reported drug Bedinvetmab (5).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Bedinvetmab appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Cat 20
Dog 7
Horse 3

Breeds Most Affected

Domestic Shorthair 13
Mixed (Cat) 3
Quarter Horse 3
Retriever - Golden 2
Retriever - Labrador 2
Scottish Fold Longhair 1
Crossbred Feline/cat 1
Cat (other) 1
Domestic Longhair 1
Beagle 1

Associated Drugs

Bedinvetmab 5
Frunevetmab 5
Gabapentin 5
Clodronate Disodium 3
Water, Sodium Chloride, Sodium Gluconate, Sodium Acetate Trihydrate, Potassium Chloride, Magnesium Chloride 3
Water, Sodium Chloride 3
Furosemide 3
Acetaminophen 3
Bexagliflozin 2
Afoxolaner 2
Moxidectin 2
Mirtazapine 2
Ondansetron 2
Methimazole 2
Benazapril 5Mg 2
Clopidogrel 18.75 Mg 2
Glucosamine 2
Fluoxtine 2.5Mg 2
Potassium Gluconate 2
Torsemide 2

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Chronic kidney disease (#1993 of 2,481 by report volume); death-coded 20.0%. PlainBreed reaction plate · report volume stamp 30 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →