Reaction profile

The FDA adverse-event record for pancreas disorder

490 FDA adverse-event reports reference pancreas disorder (VeDDRA 330). See the species, breeds, and drugs most associated with it below.

490
reports citing this reaction
50.6%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
Verify with FDA CVM →
490
Total Reports
248
Deaths
50.6%
Death Rate

Species Most Affected

Dog 384
Cat 104
Human 1
Mouse 1

Breeds Most Affected

Domestic Shorthair 57
Retriever - Labrador 33
Crossbred Canine/dog 24
Chihuahua 16
Dog (unknown) 16
Shepherd Dog - German 16
Terrier - Yorkshire 15
Maltese 12
Retriever - Golden 12
Domestic Longhair 11

Associated Drugs

Milbemycin Oxime + Spinosad 77
Maropitant Citrate 57
Spinosad 46
Carprofen 46
Oclacitinib Maleate 34
Trilostane 22
Buprenorphine 21
Cefovecin 20
Fluralaner Chew Tablets 19
Gabapentin 17
Afoxolaner 16
Isoflurane 16
Famotidine 14
Amoxicillin 13
Bedinvetmab 13
Meloxicam 12
Enrofloxacin 12
Ampicillin 12
Tramadol 12
Velagliflozin Proline Monohydrate 12

Pancreas disorder Reaction Insights

490 reports name Pancreas disorder; 248 recorded a death outcome (50.6% of reported events, not a population-level mortality rate). VeDDRA code: 330.

By species: Dog (384 reports), Cat (104 reports), Human (1 reports). By breed: Domestic Shorthair (57), Retriever - Labrador (33), Crossbred Canine/dog (24).

Most co-reported drugs: Milbemycin Oxime + Spinosad (77 reports), Maropitant Citrate (57 reports), Spinosad (46 reports), Carprofen (46 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.