Reaction profile

The FDA adverse-event record for pancreas disorder

501 FDA reports name pancreas disorder, a high-volume reaction in the CVM extract (VeDDRA 330). Plate stamps and neighbourhood peers follow.

#645 of 2,481
by report volume (all reactions)
501
reports citing this reaction
51.3%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Pancreas disorder has 501 reports now versus 498 in that prior snapshot: 3 more (0.6%).

Report change
+3
Death-coded reports
+1
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Pancreas disorder changes

FDA AER · VeDDRA plate

Code 330 VOL-MID

VOL-MID · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 501 reports
  • DEATH-HOT 51.3%
  • MID-PACK #645/2481
  • PHOTO-FINISH Application site stic…
  • SPECIES-DOG Dog · 390
  • DRUG-LEAD Milbemycin Oxime… · 77
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Application site stickiness (±1 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Pancreas disorder

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Application site ulcer · near503Device breakage/fract… · near503Application site stic… · near502Pancreas disorder · this rea…501Blepharospasm · near500Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Pancreas disorder

Pancreas disorder: high death-coded share in the FDA AER plate

Signature read: 257 death-coded reports is a heavy tail count for Pancreas disorder in the CVM extract. Report volume is upper-third scale: 501 named reports in the openFDA extract. Death-coded share is upper-third: 257 of 501 reports (51.3% of named reports). Nearest volume peer: Application site stickiness (±1 reports). Lead species Dog (390). Lead co-reported drug Milbemycin Oxime + Spinosad (77).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 390
Cat 109
Human 1
Mouse 1

Breeds Most Affected

Domestic Shorthair 61
Retriever - Labrador 35
Crossbred Canine/dog 24
Chihuahua 16
Dog (unknown) 16
Shepherd Dog - German 16
Terrier - Yorkshire 15
Retriever - Golden 12
Maltese 12
Domestic Longhair 11

Associated Drugs

Milbemycin Oxime + Spinosad 77
Maropitant Citrate 63
Spinosad 46
Carprofen 46
Oclacitinib Maleate 37
Trilostane 22
Buprenorphine 22
Cefovecin 20
Gabapentin 20
Fluralaner Chew Tablets 19
Afoxolaner 18
Famotidine 17
Isoflurane 16
Bedinvetmab 15
Enrofloxacin 13
Amoxicillin 13
Metronidazole 13
Meloxicam 12
Ampicillin 12
Tramadol 12

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Pancreas disorder, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (501 here).

Similar death-coded share

Nearest other reactions by death-coded share (51.3% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Pancreas disorder (#645 of 2,481 by report volume); death-coded 51.3%. PlainBreed reaction plate · death-coded report count stamp 257 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →