Reaction profile

The FDA adverse-event record for nerve damage nos

46 FDA adverse-event reports reference nerve damage nos (VeDDRA 1639). See the species, breeds, and drugs most associated with it below.

46
reports citing this reaction
17.4%
death-coded share
Dog
most-affected species
Carprofen
most-associated drug
Verify with FDA CVM →
46
Total Reports
8
Deaths
17.4%
Death Rate

Species Most Affected

Dog 39
Cat 5
Cattle 1
Horse 1

Breeds Most Affected

Retriever - Labrador 5
Chihuahua 4
Dog (unknown) 4
Crossbred Canine/dog 3
Schnauzer - Miniature 2
Shepherd Dog - German 2
Doberman Pinscher 2
Boxer (German Boxer) 2
Maltese 2
Domestic Longhair 1

Associated Drugs

Carprofen 7
Fluralaner Chew Tablets 6
Gabapentin 6
Milbemycin Oxime + Spinosad 6
Bedinvetmab 6
Afoxolaner 3
Pyrantel Pamoate;Sarolaner 3
Moxidectin 2
Ivermectin + Pyrantel As Pamoate Salt 2
Prednisolone 2
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 2
Maropitant Citrate 2
Trilostane 1
Spinosad 1
Praziquantel & Pyrantel Pamoate 1
Praziquantel 1
Unknown Steriods 1
Ractopamine Hydrochloride 1
Trenbolone; Estradiol; Tylosin Tartrate 1
Monensin Sodium 1

Nerve damage NOS Reaction Insights

46 reports name Nerve damage NOS; 8 recorded a death outcome (17.4% of reported events, not a population-level mortality rate). VeDDRA code: 1639.

By species: Dog (39 reports), Cat (5 reports), Cattle (1 reports). By breed: Retriever - Labrador (5), Chihuahua (4), Dog (unknown) (4).

Most co-reported drugs: Carprofen (7 reports), Fluralaner Chew Tablets (6 reports), Gabapentin (6 reports), Milbemycin Oxime + Spinosad (6 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.