Reaction profile

The FDA adverse-event record for low blood pressure

624 FDA reports name low blood pressure, a high-volume reaction in the CVM extract (VeDDRA 229). Plate stamps and neighbourhood peers follow.

#559 of 2,481
by report volume (all reactions)
624
reports citing this reaction
30.1%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Low blood pressure has 624 reports now versus 602 in that prior snapshot: 22 more (3.7%).

Report change
+22
Death-coded reports
+7
Death-coded share
+0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Low blood pressure changes

FDA AER · VeDDRA plate

Code 229 VOL-MID

VOL-MID · DEATH-HOT · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 624 reports
  • DEATH-HOT 30.1%
  • UPPER-Q #559/2481
  • PHOTO-FINISH Increased salivation
  • SPECIES-DOG Dog · 461
  • DRUG-LEAD Moxidectin · 106
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Increased salivation (±2 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Low blood pressure

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Muscle spasm NOS · near628Low blood pressure · this re…624Increased salivation · near622Labelled drug-drug in… · near622Head tilt - neurologi… · near621Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Low blood pressure

Low blood pressure: high death-coded share in the FDA AER plate

Signature read: 188 death-coded reports is a heavy tail count for Low blood pressure in the CVM extract. Report volume is upper-third scale: 624 named reports in the openFDA extract. Death-coded share is upper-third: 188 of 624 reports (30.1% of named reports). Nearest volume peer: Increased salivation (±2 reports). Lead species Dog (461). Lead co-reported drug Moxidectin (106).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 461
Cat 146
Human 12
Horse 3
Monkey 1
Lion 1

Breeds Most Affected

Domestic Shorthair 95
Retriever - Labrador 47
Crossbred Canine/dog 27
Chihuahua 24
Shih Tzu 21
Unknown 19
Terrier - Bull - American Pit 16
Retriever - Golden 14
Maltese 14
Domestic Longhair 14

Associated Drugs

Moxidectin 106
Maropitant Citrate 99
Buprenorphine 65
Isoflurane 55
Gabapentin 48
Milbemycin Oxime + Spinosad 43
Propofol 42
Butorphanol 39
Carprofen 35
Diphenhydramine 33
Robenacoxib 32
Dexmedetomidine 31
Midazolam 30
Ketamine 28
Dexmedetomidine Hydrochloride 25
Capromorelin Tartrate 25
Metronidazole 22
Epinephrine 22
Polysulfated Glycosaminoglycan 21
Prednisone 21

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Low blood pressure, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Low blood pressure (#559 of 2,481 by report volume); death-coded 30.1%. PlainBreed reaction plate · death-coded report count stamp 188 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →