Reaction profile

The FDA adverse-event record for low blood pressure

577 FDA adverse-event reports reference low blood pressure (VeDDRA 229). See the species, breeds, and drugs most associated with it below.

577
reports citing this reaction
30.7%
death-coded share
Dog
most-affected species
Moxidectin
most-associated drug
Verify with FDA CVM →
577
Total Reports
177
Deaths
30.7%
Death Rate

Species Most Affected

Dog 427
Cat 134
Human 12
Horse 3
Monkey 1

Breeds Most Affected

Domestic Shorthair 87
Retriever - Labrador 43
Chihuahua 22
Crossbred Canine/dog 22
Shih Tzu 20
Unknown 18
Terrier - Bull - American Pit 15
Maltese 14
Retriever - Golden 13
Dog (unknown) 12

Associated Drugs

Moxidectin 97
Maropitant Citrate 82
Buprenorphine 61
Isoflurane 49
Milbemycin Oxime + Spinosad 43
Gabapentin 42
Propofol 41
Butorphanol 37
Carprofen 31
Robenacoxib 30
Dexmedetomidine 29
Diphenhydramine 28
Midazolam 27
Ketamine 26
Capromorelin Tartrate 25
Dexmedetomidine Hydrochloride 22
Prednisone 21
Famotidine 21
Polysulfated Glycosaminoglycan 20
Dexamethasone 20

Low blood pressure Reaction Insights

577 reports name Low blood pressure; 177 recorded a death outcome (30.7% of reported events, not a population-level mortality rate). VeDDRA code: 229.

By species: Dog (427 reports), Cat (134 reports), Human (12 reports). By breed: Domestic Shorthair (87), Retriever - Labrador (43), Chihuahua (22).

Most co-reported drugs: Moxidectin (97 reports), Maropitant Citrate (82 reports), Buprenorphine (61 reports), Isoflurane (49 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.