Reaction profile

The FDA adverse-event record for tracheal collapse

169 FDA adverse-event reports reference tracheal collapse (VeDDRA 879). See the species, breeds, and drugs most associated with it below.

169
reports citing this reaction
32.0%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
Verify with FDA CVM →
169
Total Reports
54
Deaths
32.0%
Death Rate

Species Most Affected

Dog 168
Cat 1

Breeds Most Affected

Terrier - Yorkshire 26
Chihuahua 17
Maltese 16
Spitz - German Pomeranian 16
Pug 9
Crossbred Canine/dog 9
Shih Tzu 8
Poodle - Miniature 4
Schnauzer - Miniature 4
Poodle - Toy 4

Associated Drugs

Milbemycin Oxime + Spinosad 39
Trilostane 27
Oclacitinib Maleate 19
Gabapentin 13
Maropitant Citrate 11
Ivermectin + Pyrantel As Pamoate Salt 10
Pimobendan 9
Hydrocodone 8
Grapiprant 8
Bedinvetmab 8
Prednisone 7
Afoxolaner 7
Milbemycin Oxime + Praziquantel 7
Meloxicam 6
Fluralaner 13.64% 12-Week Chew 6
Moxidectin 6
Fluralaner Chew Tablets 5
Dexamethasone 5
Trazadone 5
Milbemycin Oxime 4

Tracheal collapse Reaction Insights

169 reports name Tracheal collapse; 54 recorded a death outcome (32.0% of reported events, not a population-level mortality rate). VeDDRA code: 879.

By species: Dog (168 reports), Cat (1 reports). By breed: Terrier - Yorkshire (26), Chihuahua (17), Maltese (16).

Most co-reported drugs: Milbemycin Oxime + Spinosad (39 reports), Trilostane (27 reports), Oclacitinib Maleate (19 reports), Gabapentin (13 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.