Reaction profile

The FDA adverse-event record for unable to chew

35 FDA adverse-event reports reference unable to chew (VeDDRA 2451). See the species, breeds, and drugs most associated with it below.

35
reports citing this reaction
8.6%
death-coded share
Dog
most-affected species
Gabapentin
most-associated drug
Verify with FDA CVM →
35
Total Reports
3
Deaths
8.6%
Death Rate

Species Most Affected

Dog 21
Cat 7
Horse 5
Unknown 2

Breeds Most Affected

Domestic Shorthair 6
Retriever - Labrador 5
Shepherd Dog - Australian 3
Unknown 2
Thoroughbred 2
Dog (unknown) 2
Cat (other) 1
Mixed (Dog) 1
Quarter Horse 1
Miniature 1

Associated Drugs

Gabapentin 5
Maropitant Citrate 4
Bedinvetmab 4
Fluid Therapy 3
Trilostane 3
Milbemycin Oxime + Spinosad 2
Buprenorphine 2
Ivermectin + Praziquantel 2
Florfenicol/Terbinafine Hydrochloride/Mometasone Furoate 2
Pergolide Mesylate 2
Imidacloprid + Moxidectin 2
Canine Parvovirus Strain Nl-35-D, P.35-D, 8-2-80;Canine Parainfluenza Virus, Str 2
Bordetella Bronchiseptica 92B 012992-7 Strain Boehringer Ingelheim 2
Rabacfosadine 2
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 2
Prednisone 2
Selamectin 2
Methocarbamol 2
Bexagliflozin 2
Robenacoxib 2

Unable to chew Reaction Insights

35 reports name Unable to chew; 3 recorded a death outcome (8.6% of reported events, not a population-level mortality rate). VeDDRA code: 2451.

By species: Dog (21 reports), Cat (7 reports), Horse (5 reports). By breed: Domestic Shorthair (6), Retriever - Labrador (5), Shepherd Dog - Australian (3).

Most co-reported drugs: Gabapentin (5 reports), Maropitant Citrate (4 reports), Bedinvetmab (4 reports), Fluid Therapy (3 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.