Reaction profile

The FDA adverse-event record for cystitis

325 FDA adverse-event reports reference cystitis (VeDDRA 725). See the species, breeds, and drugs most associated with it below.

325
reports citing this reaction
16.6%
death-coded share
Dog
most-affected species
Oclacitinib Maleate
most-associated drug
Verify with FDA CVM →
325
Total Reports
54
Deaths
16.6%
Death Rate

Species Most Affected

Dog 241
Cat 82
Rat 1
Cattle 1

Breeds Most Affected

Domestic Shorthair 45
Retriever - Labrador 26
Crossbred Canine/dog 19
Retriever - Golden 11
Shih Tzu 10
Terrier - Bull - American Pit 9
Boxer (German Boxer) 8
Dog (unknown) 8
Dachshund (unspecified) 7
Shepherd Dog - German 7

Associated Drugs

Oclacitinib Maleate 68
Bedinvetmab 28
Trilostane 24
Carprofen 21
Milbemycin Oxime + Spinosad 21
Frunevetmab 14
Spinosad 13
Maropitant Citrate 12
Buprenorphine 12
Enrofloxacin 12
Propofol 12
Robenacoxib 11
Gabapentin 11
Selamectin 10
Cefovecin 9
Cefovecin Sodium 8
Cefpodoxime Proxetil 8
Afoxolaner 8
Butorphanol 8
Cyclosporine 7

Cystitis Reaction Insights

325 reports name Cystitis; 54 recorded a death outcome (16.6% of reported events, not a population-level mortality rate). VeDDRA code: 725.

By species: Dog (241 reports), Cat (82 reports), Rat (1 reports). By breed: Domestic Shorthair (45), Retriever - Labrador (26), Crossbred Canine/dog (19).

Most co-reported drugs: Oclacitinib Maleate (68 reports), Bedinvetmab (28 reports), Trilostane (24 reports), Carprofen (21 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.