Reaction profile

The FDA adverse-event record for licking at injection site

263 FDA adverse-event reports reference licking at injection site (VeDDRA 2752). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#915 of 2,481
by report volume (all reactions)
263
reports citing this reaction
4.9%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Licking at injection site has 263 reports now versus 253 in that prior snapshot: 10 more (4.0%).

Report change
+10
Death-coded reports
+0
Death-coded share
−0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Licking at injection site changes

FDA AER · VeDDRA plate

Code 2752 VOL-LOW

VOL-LOW · DEATH-LOW · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 263 reports
  • DEATH-LOW 4.9%
  • MID-PACK #915/2481
  • PHOTO-FINISH Hyperaemic mucous mem…
  • SPECIES-DOG Dog · 241
  • DRUG-LEAD Tigilanol Tiglate · 187
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Hyperaemic mucous membrane (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Licking at injection site

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Hyperaemic mucous mem… · near263Impaired vocalisation · near263Licking at injection… · this…263Attention-seeking beh… · near262Histiocytoma · near262Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Licking at injection site

Licking at injection site: low death-coded share in the FDA AER plate

Signature read: Licking at injection site's 4.9% death-coded share is among the lowest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is lower-third: 13 of 263 reports (4.9% of named reports). Nearest volume peer: Hyperaemic mucous membrane (±0 reports). Lead species Dog (241). Lead co-reported drug Tigilanol Tiglate (187).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Tigilanol Tiglate appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 241
Cat 21
Other Birds 1

Breeds Most Affected

Retriever - Labrador 41
Retriever - Golden 20
Dog (unknown) 17
Boxer (German Boxer) 15
Pit Bull 13
Domestic Shorthair 13
Bulldog - French 11
Terrier (unspecified) 11
Chihuahua 11
Shepherd Dog - German 10

Associated Drugs

Tigilanol Tiglate 187
Diphenhydramine 56
Famotidine 51
Prednisone 49
Gabapentin 45
Butorphanol 44
Maropitant Citrate 38
Dexmedetomidine 33
Atipamezole 30
Atipamezole Hydrochloride 21
Butorphanol Tartrate 21
Dexmedetomidine Hydrochloride 19
Buprenorphine 19
Carprofen 18
Propofol 17
Hydromorphone 16
Ketamine 12
Frunevetmab 10
Trazodone 8
Bedinvetmab 8

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Licking at injection site, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (263 here).

Similar death-coded share

Nearest other reactions by death-coded share (4.9% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Licking at injection site (#915 of 2,481 by report volume); death-coded 4.9%. PlainBreed reaction plate · death-coded share stamp 4.9% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →