Reaction profile

The FDA adverse-event record for high thyroid stimulating hormone (tsh)

39 FDA reports name high thyroid stimulating hormone (tsh), a lower-volume reaction in the CVM extract (VeDDRA 2703). Plate stamps and neighbourhood peers follow.

#1861 of 2,481
by report volume (all reactions)
39
reports citing this reaction
5.1%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. High thyroid stimulating hormone (TSH) has 39 reports now versus 37 in that prior snapshot: 2 more (5.4%).

Report change
+2
Death-coded reports
+0
Death-coded share
−0.3 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to High thyroid stimulating hormone (TSH) changes

FDA AER · VeDDRA plate

Code 2703 VOL-TRACE

VOL-TRACE · DEATH-PAR · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 39 reports
  • DEATH-PAR 5.1%
  • MID-PACK #1861/2481
  • PHOTO-FINISH Adaptor, missing
  • SPECIES-DOG Dog · 34
  • DRUG-LEAD Trilostane · 9
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Adaptor, missing (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around High thyroid stimulating hormone

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Adaptor, missing · near39Adrenal gland tumour · near39Cardiopathy · near39CAT SCAN ABNORMAL · near39High thyroid stimulat… · thi…39Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around High thyroid stimulating hormone (TSH)

High thyroid stimulating hormone (TSH): low death-coded share in the FDA AER plate

Signature read: 2 death-coded reports is a thin tail count for High thyroid stimulating hormone (TSH) in the CVM extract. Report volume is lower-third scale: 39 named reports in the openFDA extract. Death-coded share is lower-third: 2 of 39 reports (5.1% of named reports). Nearest volume peer: Adaptor, missing (±0 reports). Lead species Dog (34). Lead co-reported drug Trilostane (9).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Trilostane appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 34
Cat 4
Human 1

Breeds Most Affected

Retriever - Labrador 4
Domestic Shorthair 3
Schnauzer - Miniature 3
Beagle 3
Dachshund - Standard Long-haired 3
Spitz - American Eskimo Dog 2
Crossbred Canine/dog 2
Terrier - Bull - American Pit 2
Mixed (Dog) 2
Dachshund (unspecified) 2

Associated Drugs

Trilostane 9
Gabapentin 6
Bedinvetmab 6
Oclacitinib Maleate 5
Anti-Il31 Mab Mcs Lot #1283563 4
Levothyroxine Sodium 3
Insulin Injectable Vial 3
Fluralaner 13.64% 12-Week Chew 3
Thiamazole 2
S-Adenosylmethionine + Silybin 2
Maropitant Citrate 2
Levothyroxine Sodium, Usp 2
Fluralaner 2
Afoxolaner 2
Frunevetmab 2
Penobarbital 2
Levothyroxine 2
Trazodone 2
Melatonin 2
Ilunocitinib 2

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for High thyroid stimulating hormone (TSH) (#1861 of 2,481 by report volume); death-coded 5.1%. PlainBreed reaction plate · death-coded report count stamp 2 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →