Reaction profile

The FDA adverse-event record for schirmer tear test

200 FDA adverse-event reports reference schirmer tear test (VeDDRA 2666). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1035 of 2,481
by report volume (all reactions)
200
reports citing this reaction
3.0%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Schirmer tear test has 200 reports now versus 200 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Schirmer tear test changes

FDA AER · VeDDRA plate

Code 2666 VOL-LOW

VOL-LOW · DEATH-LOW · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 200 reports
  • DEATH-LOW 3.0%
  • MID-PACK #1035/2481
  • PHOTO-FINISH Low serum alkaline ph…
  • SPECIES-DOG Dog · 199
  • DRUG-LEAD Florfenicol + Mom… · 144
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Low serum alkaline phosphatase (ALP) (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Schirmer tear test

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Low serum alkaline ph… · near200PR-SPLEEN, LESION(S) · near200Schirmer tear test · this re…200Anal and rectal disor… · near199Calculi · near199Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Schirmer tear test

Schirmer tear test: low death-coded share in the FDA AER plate

Signature read: Schirmer tear test's 3.0% death-coded share is among the lowest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is lower-third: 6 of 200 reports (3.0% of named reports). Nearest volume peer: Low serum alkaline phosphatase (ALP) (±0 reports). Lead species Dog (199). Lead co-reported drug Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride (144).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 199
Cat 1

Breeds Most Affected

Chihuahua 27
Shih Tzu 17
Maltese 15
Terrier - Yorkshire 15
Crossbred Canine/dog 11
Dachshund (unspecified) 7
Spaniel - King Charles Cavalier 7
Havanese 6
Shiba Inu 6
Retriever - Golden 6

Associated Drugs

Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 144
Maropitant Citrate 37
Pilocarpine 27
Florfenicol, Terbinafine, Betamethasone Acetate 26
Ear Cleaner 22
Carprofen 19
Prednisone 18
Gabapentin 16
Artificial Tears 14
Enrofloxacin 13
Eye Lubricant 12
Ofloxacin 11
Fluids 9
Cyclosporine 9
Ear Cleaner (Unknown) 9
Tacrolimus 8
Meloxicam 8
Tramadol 7
Tobramycin 7
Moxidectin 7

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Schirmer tear test, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (3.0% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Schirmer tear test (#1035 of 2,481 by report volume); death-coded 3.0%. PlainBreed reaction plate · death-coded share stamp 3.0% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →