Reaction profile

The FDA adverse-event record for decreased drinking

1,250 FDA reports name decreased drinking, a high-volume reaction in the CVM extract (VeDDRA 2500). Plate stamps and neighbourhood peers follow.

#328 of 2,481
by report volume (all reactions)
1,250
reports citing this reaction
13.1%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Decreased drinking has 1,250 reports now versus 1,214 in that prior snapshot: 36 more (3.0%).

Report change
+36
Death-coded reports
+2
Death-coded share
−0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Decreased drinking changes

FDA AER · VeDDRA plate

Code 2500 VOL-MID

VOL-MID · DEATH-ELEV · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 1,250 reports
  • DEATH-ELEV 13.1%
  • UPPER-Q #328/2481
  • PHOTO-FINISH Tense abdomen
  • SPECIES-DOG Dog · 937
  • DRUG-LEAD Fluralaner Chew T… · 102
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Tense abdomen (±6 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Decreased drinking

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Respiratory distress · near1259Tense abdomen · near1256Decreased drinking · this re…1250Sudden death · near1241Flatulence · near1238Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Decreased drinking

What the FDA AER plate says about Decreased drinking

Signature read: 1,250 reports place Decreased drinking in the upper third of FDA AER volume (#328 of 2,481). Report volume is upper-third scale: 1,250 named reports in the openFDA extract. 164 of 1,250 reports were death-coded (13.1% of named reports, not a population mortality rate). Nearest volume peer: Tense abdomen (±6 reports). Lead species Dog (937). Lead co-reported drug Fluralaner Chew Tablets (102).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Fluralaner Chew Tablets appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 937
Cat 292
Horse 9
Chicken 4
Rabbit 3
Cattle 2
Pig 2
Turkey 1

Breeds Most Affected

Domestic Shorthair 187
Retriever - Labrador 106
Crossbred Canine/dog 104
Chihuahua 51
Shih Tzu 46
Retriever - Golden 36
Shepherd Dog - German 33
Terrier - Yorkshire 32
Maltese 31
Pit Bull 24

Associated Drugs

Fluralaner Chew Tablets 102
Trilostane 93
Fluralaner 13.64% 12-Week Chew 76
Maropitant Citrate 72
Pyrantel Pamoate;Sarolaner 61
Carprofen 59
Cefovecin 58
Afoxolaner 56
Bedinvetmab 51
Moxidectin 46
Gabapentin 44
Buprenorphine 43
Fluralaner Spot-On Solution 40
Milbemycin Oxime + Praziquantel 39
Oclacitinib Maleate 38
Milbemycin Oxime + Spinosad 37
Selamectin 33
Prednisone 31
Sarolaner 31
Nitenpyram 29

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Decreased drinking, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (1,250 here).

Similar death-coded share

Nearest other reactions by death-coded share (13.1% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Decreased drinking (#328 of 2,481 by report volume); death-coded 13.1%. PlainBreed reaction plate · report volume stamp 1,250 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →