Lack of efficacy (heartworm)
VeDDRA Code: 2430
1,001 adverse event reports referencing this reaction
1,001
Total Reports
10
Deaths
100.0%
Death Rate
Species Most Affected
Dog 1,000
Cat 1
Breeds Most Affected
Retriever - Labrador 226
Shepherd Dog - German 74
Crossbred Canine/dog 74
Beagle 41
Dog (unknown) 38
Pit Bull 37
Retriever - Golden 30
Boxer (German Boxer) 27
Terrier (unspecified) 26
Shepherd Dog - Australian 24
Associated Drugs
Milbemycin Oxime + Praziquantel 345
Lufenuron + Milbemycin Oxime 338
Lufenuron + Milbemycin Oxime + Praziquantel 199
Moxidectin 162
Milbemycin Oxime 86
Ivermectin + Pyrantel Pamoate 56
Milbemycin Oxime + Spinosad 52
Ivermectin 49
Selamectin 45
Ivermectin + Pyrantel As Pamoate Salt 33
Ivermectin/Pyrantel 31
Melarsomine Dihydrochloride 24
Afoxolaner 19
Ivermectin + Praziquantel + Pyrantel Pamoate 19
Fluralaner 18
Doxycycline 18
Milbemycin Oxime + Lufenuron 11
Spinosad/Milbemycin Oxime 10
Imidacolprid And Moxidectin 9
Prednisone 9
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.